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Related parties
6 Months Ended
Jun. 30, 2021
Related Party Transactions [Abstract]  
Related Parties

14.

Related parties

A member of our Board of Directors, J. Martin Carrol, is also a director of Catalent. From time to time, we have entered into agreements with Catalent and its affiliates in the normal course of business. Agreements with Catalent have been reviewed by independent directors of our Company, or a committee consisting of independent directors of our Company. For manufacturing activities, Catalent billed us $0.7 million for the three months ended June 30, 2021 and 2020, and $1.5 million and $2.0 million for the six months ended June 30, 2021 and 2020, respectively. As of June 30, 2021 and December 31, 2020, we have estimated amounts payable to Catalent totaling $0.3 million. In addition, we have minimum purchase requirements in place with Catalent as disclosed in Note 9, Commitments and contingencies.

A member of our Board of Directors, Karen L. Ling, was an executive vice president and chief human resources officer of American International Group, Inc. (“AIG”). From time to time, we have entered into agreements with AIG in the normal course of business. Agreements with AIG have been reviewed by independent directors of our Company, or a committee consisting of independent directors of our Company. For various insurance premiums, AIG billed us less than $0.1 million for the three and six months ended June 30, 2021, and $0.1 million for the three and six months ended June 30, 2020.  As of June 30, 2021 and December 31, 2020, we have no amounts payable to AIG.