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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
CASH FLOWS FROM OPERATING ACTIVITIES      
Net loss $ (89,875,459) $ (85,077,024) $ (54,217,210)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation 77,906 29,959 28,987
Amortization of intangible assets 54,545 32,441 23,480
Provision for (recovery of) doubtful accounts 2,524,909 22,157 (5,436)
Share-based compensation 17,411,021 7,189,699 4,970,312
Amortization of deferred financing costs 260,027
Changes in operating assets and liabilities:      
Accounts receivable (3,975,893) (917,656) (458,028)
Inventory (386,168) 491,960 (138,495)
Other current assets 709,907 (773,532) 680,281
Other assets (17,442) (37,309)
Accounts payable 4,232,340 (3,200,955) 4,212,912
Deferred revenue (522,613) (1,079,967)
Other current liabilities 84,559 3,698,887 239,450
Net cash used in operating activities (69,142,333) (79,044,119) (45,520,996)
CASH FLOWS FROM INVESTING ACTIVITIES      
Patent costs (845,266) (419,104) (586,480)
Purchase of fixed assets (396,154) (165,257) (30,962)
(Payment) refund of security deposit (14,036) 10,686
Net cash used in investing activities (1,255,456) (584,361) (606,756)
CASH FLOWS FROM FINANCING ACTIVITIES      
Proceeds from sale of common stock, net of costs 134,863,475 91,374,649 42,771,353
Proceeds from exercise of options 989,060 1,232,579 345,746
Proceeds from exercise of warrants 1,373,000 366,000 181,000
Net cash provided by financing activities 137,225,535 92,973,228 43,298,099
Increase (decrease) in cash 66,827,746 13,344,748 (2,829,653)
Cash, beginning of period 64,706,355 51,361,607 54,191,260
Cash, end of period $ 131,534,101 $ 64,706,355 $ 51,361,607