CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income Statement [Abstract]
Revenues, net	$ 19,356,450	$ 20,142,898	$ 15,026,219
Cost of goods sold	4,185,708	4,506,673	3,671,803
Gross profit	15,170,742	15,636,225	11,354,416
Operating expenses:
Sales, general, and administrative	51,348,414	28,721,236	22,124,072
Research and development	53,943,477	72,042,774	43,218,938
Depreciation and amortization	132,451	62,400	52,467
Total operating expenses	105,424,342	100,826,410	65,395,477
Operating loss	(90,253,600)	(85,190,185)	(54,041,061)
Other income and (expense)
Miscellaneous income	367,317	95,719	46,569
Accreted interest	10,824	17,442	37,309
Financing costs			(260,027)
Total other income (expense)	378,141	113,161	(176,149)
Loss before income taxes	(89,875,459)	(85,077,024)	(54,217,210)
Net loss	$ (89,875,459)	$ (85,077,024)	$ (54,217,210)
Loss per share, basic and diluted:
Net loss per share, basic and diluted	$ (0.46)	$ (0.49)	$ (0.36)
Weighted average number of common shares outstanding, basic and diluted	196,088,196	173,174,229	149,727,228