<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2009-01-20</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000022872</issuerCik>
        <issuerName>COMPREHENSIVE CARE CORP</issuerName>
        <issuerTradingSymbol>CHCR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001454919</rptOwnerCik>
            <rptOwnerName>Husted Peggy A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>3405 W DR MARTIN LUTHER KING, JR BLVD</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 101</rptOwnerStreet2>
            <rptOwnerCity>TAMPA</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33607</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Series B1 Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1254353</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series B2 Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1995959</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The Reporting Person acquired 461.33475 shares of the Issuer's Series B1 Preferred Stock in exchange for her holdings of Core Corporate Consulting Group, Inc., which was acquired by the Issuer pursuant to a Merger Agreement.  Upon the occurrence of certain conditions set forth in the Merger Agreement, which the Issuer expects to occur within 60 days of the date of this Form 3, the Series B1 Preferred Stock may be convertible into 3,966 shares of the Issuer's Series C Preferred Stock which in turn may further convert into 1,254,353 shares of common stock of the Issuer.  The conversion feature has no expiration date.</footnote>
        <footnote id="F2">The Reporting Person acquired 734.00424 shares of the Issuer's Series B2 Preferred Stock in exchange for her holdings of Core Corporate Consulting Group, Inc., which was acquired by the Issuer pursuant to a Merger Agreement.  Upon the occurrence of certain conditions set forth in the Merger Agreement, which the Issuer expects to occur within 60 days of the date of this Form 3, the Series B2 Preferred Stock will convert into 1,995,959 shares of common stock of the Issuer.  The conversion feature has no expiration date.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Scott Bates as attorney-in-fact for Peggy A. Husted</signatureName>
        <signatureDate>2009-01-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
