X0201 4 2003-09-22 0 0001018710 INTROGEN THERAPEUTICS INC INGN 0000217028 AVENTIS INC 0 0 1 0 Common Stock 2003-09-22 4 S 0 33450 10.76 D 2736643 I 1 Common Stock 2003-09-23 4 S 0 34700 10.76 D 2701943 I 1 Owned directly by Aventis Holdings Inc. and beneficially owned by Aventis Inc. Note: On the Form 4 report filed by the Reporting Person on September 12, 2003, the number of shares of Issuer's Common Stock reported as beneficially following the transactions reported thereby was incorrectly reported as 3,860,293 as of September 10, 2003 instead of 3,820,293, and was incorrectly reported as 3,560,293 as of September 11, 2003 instead of 3,520,293. /s/ Gerald P. Belle, President 2003-09-24