X0202 SCHEDULE 13G 0001283718 XXXXXXXX LIVE Common Stock, $0.00001 par value per share 06/30/2026 0002096997 Kailera Therapeutics, Inc. 482931102 180 Third Avenue, 4th Floor Waltham MA 02451 Rule 13d-1(d) CPP Investment Board Private Holdings (4) Inc. Z4 0 7304688 0 7304688 7304688 N 5.6 CO Item 11 is calculated based on a total of 129,565,608 shares of common stock of the issuer outstanding as of May 20, 2026, as disclosed in the issuer's Form 10-Q filed with the SEC on May 26, 2026. Shares reported on this Schedule 13G are held directly by CPP Investment Board Private Holdings (4) Inc., a wholly-owned subsidiary of Canada Pension Plan Investment Board. Canada Pension Plan Investment Board Z4 0 7304688 0 7304688 7304688 N 5.6 FI Item 11 is calculated based on a total of 129,565,608 shares of common stock of the issuer outstanding as of May 20, 2026, as disclosed in the issuer's Form 10-Q filed with the SEC on May 26, 2026. Shares reported on this Schedule 13G are held directly by CPP Investment Board Private Holdings (4) Inc., a wholly-owned subsidiary of Canada Pension Plan Investment Board. Kailera Therapeutics, Inc. 180 Third Avenue, 4th Floor Waltham, MA 02451 Each of the following is hereinafter individually referred to as a "Reporting Person" and collectively as the "Reporting Persons." This statement is filed on behalf of: Canada Pension Plan Investment Board CPP Investment Board Private Holdings (4) Inc. The principal business address of each of the Reporting Persons is as follows: One Queen Street East Suite 2500 Toronto, Ontario M5C 2W5 Canada Each of the Reporting Persons is organized under the laws of Canada. Y See Item 9 on the cover pages. The securities reported herein are directly held by CPP Investment Board Private Holdings (4) Inc., a wholly-owned subsidiary of Canada Pension Plan Investment Board. As such, the Reporting Persons may be deemed to have shared voting power and dispositive power with respect to such securities. See Item 11 on the cover pages. See Item 5 on the cover pages. See Item 6 on the cover pages. See Item 7 on the cover pages. See Item 8 on the cover pages. Y Y Y Y Y Y 99.1 Power of Attorney of Canada Pension Plan Investment Board 99.2 Joint Filing Agreement CPP Investment Board Private Holdings (4) Inc. /s/ Pierre Abinakle 08/14/2026 Canada Pension Plan Investment Board /s/ Howard Rusak 08/14/2026 See Exhibit 99.1 Power of Attorney of Canada Pension Plan Investment Board