4D MOLECULAR THERAPEUTICS IN COM 35104E100 BBG00QG40S04 12130157 1302917 SH SOLE 1302917 0 0 ARCUS BIOSCIENCES INC COM 03969F109 BBG00DQD2751 22635396 1047935 SH SOLE 1047935 0 0 CAMP4 THERAPEUTICS CORP COM 13463J101 BBG00L2CHQ99 8553472 1939563 SH SOLE 1939563 0 0 CENTURY THERAPEUTICS INC COM 15673T100 BBG00PM8N5Y8 5536984 2449993 SH SOLE 2449993 0 0 CYTOKINETICS INC COM NEW 23282W605 BBG001SGMVF2 19773000 300000 SH SOLE 300000 0 0 DEFINIUM THERAPEUTICS INC COM SHS 24477V105 BBG001TCSL84 32850280 1738110 SH SOLE 1738110 0 0 DESIGN THERAPEUTICS INC COM 25056L103 BBG00SNC49W7 9065418 852013 SH SOLE 852013 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 BBG00YYCXG54 20580300 682597 SH SOLE 682597 0 0 IMMUNOVANT INC COM 45258J102 BBG00P5MC0R7 10285102 414054 SH SOLE 414054 0 0 INHIBIKASE THERAPEUTICS INC COM NEW 45719W205 BBG005TP2348 13536340 8057345 SH SOLE 8057345 0 0 INVENTIVA SA ADS 46124U107 BBG00VM4C3W3 14751883 2657997 SH SOLE 2657997 0 0 LB PHARMACEUTICALS INC COM SHS 50180M108 BBG00XNP5MR3 32535467 1319362 SH SOLE 1319362 0 0 MINERVA NEUROSCIENCES INC COM NEW 603380205 BBG0067S9Z82 8549475 1419000 SH SOLE 1419000 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 BBG00MH7T2N6 30791363 333312 SH SOLE 333312 0 0 NEUROGENE INC COM 64135M105 BBG005Y0QF99 15780986 782787 SH SOLE 782787 0 0 NURIX THERAPEUTICS INC COM 67080M103 BBG00SDJ8M87 27019910 1743220 SH SOLE 1743220 0 0 OPUS GENETICS INC COM 67577R102 BBG001SC04V7 2275000 500000 SH SOLE 500000 0 0 PROMIS NEUROSCIENCES INC COM SHS 74346M505 BBG001SMDG62 7075208 557103 SH SOLE 557103 0 0 REVOLUTION MEDICINES INC COM 76155X100 BBG00829F4Q7 23826250 245000 SH SOLE 245000 0 0 SENSEI BIOTHERAPEUTICS INC COM NEW 81728A207 BBG00V3M3TR3 3940000 125000 SH SOLE 125000 0 0 SOL-GEL TECHNOLOGIES LTD SHS NEW M8694L137 BBG00HLD5J94 6772993 85496 SH SOLE 85496 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 BBG001T92272 16394539 701821 SH SOLE 701821 0 0 VAXCYTE INC COM 92243G108 BBG009PHHPP4 38496132 662470 SH SOLE 662470 0 0 VTV THERAPEUTICS INC CL A NEW 918385204 BBG009DT9XK8 5535663 139578 SH SOLE 139578 0 0 X4 PHARMACEUTICALS INC COM NEW 98420X202 BBG001TCY1B7 10620204 2571478 SH SOLE 2571478 0 0 XENON PHARMACEUTICALS INC COM 98420N105 BBG002VBMLS5 25586000 440000 SH SOLE 440000 0 0 XENON PHARMACEUTICALS INC COM 98420N105 BBG002VBMLS5 11630000 200000 SH Put SOLE 200000 0 0