X0508 4 2025-05-28 0001492422 Apellis Pharmaceuticals, Inc. APLS 0002070437 Boucher Kelley C/O APELLIS PHARMACEUTICALS, INC. 100 FIFTH AVENUE, 3RD FLOOR WALTHAM MA 02451 1 Chief People Officer 0 Common Stock 2025-05-28 4 A 0 22087 0 A 22087 D Stock Option (Right to Buy) 16.80 2025-05-28 4 A 0 32976 16.80 A 2035-05-28 Common Stock 32976 32976 D This restricted stock unit was granted on May 28, 2025. The restricted stock unit will fully vest on the first anniversary of the date of grant, subject to her continued service as an officer, or upon later termination of her service. This represents a stock option award granted May 28, 2025 that vests over a four-year period. 25% vests one year from grant date and the remaining 75% vests monthly thereafter subject to continued service. /s/ David Watson, attorney-in-fact for Kelley Boucher 2025-05-29