144 0002069917 XXXXXXXX LIVE 0000891478 Banco Santander, S.A. 001-12518 Ciudad Grupo Santander Boadilla del Monte Madrid U3 28660 34-91-259-6520 David Hazell Chief Compliance Officer American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each Fidelity Brokerage Services LLC

PO Box 28019 Albuquerque NM 87124

4370 34610.00 15152492322 05/13/2025 NYSE American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each Fidelity Brokerage Services LLC

PO Box 28019 Albuquerque NM 87124

36660 290347.00 15152492322 05/13/2025 NYSE American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each 03/26/2024 Equity compensation under the 2021 plan Issuer N 3494 03/26/2024 Compensation American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each 03/14/2024 Equity compensation under the 2021 plan Issuer N 3747 03/14/2024 Compensation American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each 03/14/2024 Equity compensation under the 2024 plan Issuer N 20637 03/14/2024 Compensation American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each 03/14/2024 Equity compensation under the 2023 plan Issuer N 4118 03/14/2024 Compensation American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each 03/14/2024 Equity compensation under the 2022 plan Issuer N 5541 03/14/2024 Compensation American Depositary Shares, each representing the right to receive one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each 04/27/2023 Equity compensation under the 2021 plan Issuer N 3493 04/27/2023 Compensation N David Hazell

Ciudad Grupo Santander Boadilla del Monte Madrid U3 28660

Crest Depository Interests (CDIs), each representing one Share of Capital Stock of Banco Santander, S.A., par value euro 0.50 each. 05/13/2025 1132 6544.23 05/26/2025 /s/ David Hazell