<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2025-06-30</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0002055879</issuerCik>
        <issuerName>Vendome Acquisition Corp I</issuerName>
        <issuerTradingSymbol>VNME</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002074898</rptOwnerCik>
            <rptOwnerName>Vendome Acquisition Sponsor I LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VENDOME ACQUISITION CORPORATION I</rptOwnerStreet1>
            <rptOwnerStreet2>1090 CENTER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>PARK CITY</rptOwnerCity>
            <rptOwnerState>UT</rptOwnerState>
            <rptOwnerZipCode>84098</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0002074896</rptOwnerCik>
            <rptOwnerName>Vendome Acquisition Holding I LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VENDOME ACQUISITION CORPORATION I</rptOwnerStreet1>
            <rptOwnerStreet2>1090 CENTER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>PARK CITY</rptOwnerCity>
            <rptOwnerState>UT</rptOwnerState>
            <rptOwnerZipCode>84098</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001113835</rptOwnerCik>
            <rptOwnerName>KESSLER PAUL L.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VENDOME ACQUISITION CORPORATION I</rptOwnerStreet1>
            <rptOwnerStreet2>1090 CENTER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>PARK CITY</rptOwnerCity>
            <rptOwnerState>UT</rptOwnerState>
            <rptOwnerZipCode>84098</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001281112</rptOwnerCik>
            <rptOwnerName>KESSLER DIANA DERYCZ</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VENDOME ACQUISITION CORPORATION I</rptOwnerStreet1>
            <rptOwnerStreet2>1090 CENTER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>PARK CITY</rptOwnerCity>
            <rptOwnerState>UT</rptOwnerState>
            <rptOwnerZipCode>84098</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>true</isOfficer>
            <officerTitle>President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001159806</rptOwnerCik>
            <rptOwnerName>LAPORTA SCOTT A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VENDOME ACQUISITION CORPORATION I</rptOwnerStreet1>
            <rptOwnerStreet2>1090 CENTER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>PARK CITY</rptOwnerCity>
            <rptOwnerState>UT</rptOwnerState>
            <rptOwnerZipCode>84098</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>true</isOfficer>
            <officerTitle>Chief Executive Officer, CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Class B ordinary shares</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Class A ordinary shares</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>5675000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">As described in the issuer's registration statement on Form S-1 (File No. 333-285534) under the heading &quot;Description of Securities - Founder Shares&quot;, the Class B ordinary shares will automatically convert into Class A ordinary shares at the time of the issuer's initial business combination, on a one-for-one basis, subject to adjustment for stock splits, stock dividends, reorganizations, recapitalizations and the like, and certain anti-dilution rights and has no expiration date.</footnote>
        <footnote id="F2">Reflects securities held directly by Vendome Acquisition Sponsor I LLC (the &quot;Sponsor &quot;). Ms. Diana Derycz-Kessler, President, Paul Kessler, Executive Chairman, and Scott La Porta, Chief Executive Officer and Chief Financial Officer, are the sole members of Vendome Acquisition Holding I LLC, the managing member of the Sponsor. As such, they may be deemed to have or share beneficial ownership of the Class B ordinary shares held directly by Vendome Acquisition Sponsor I LLC. Such persons disclaim any beneficial ownership of the reported shares other than to the extent of any pecuniary interest he may have therein, directly or indirectly.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Scott A. LaPorta, as Authorized Signatory of Vendome Acquisition Sponsor I LLC</signatureName>
        <signatureDate>2025-06-30</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/Scott A. LaPorta, as Authorized Signatory of Vendome Acquisition Holding I LLC</signatureName>
        <signatureDate>2025-06-30</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Paul Kessler</signatureName>
        <signatureDate>2025-06-30</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Diana Derycz-Kessler</signatureName>
        <signatureDate>2025-06-30</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Scott A. LaPorta</signatureName>
        <signatureDate>2025-06-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
