<?xml version="1.0" encoding="UTF-8"?>
<edgarSubmission xmlns="http://www.sec.gov/edgar/seventeenafiler" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>X-17A-5</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <filerCik>0000205307</filerCik>
          <filerCcc>XXXXXXXX</filerCcc>
        </filerCredentials>
        <confirming008CopyNumber>008-21025</confirming008CopyNumber>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>
      <flags>
        <returnCopyFlag>false</returnCopyFlag>
        <confirmingCopyFlag>true</confirmingCopyFlag>
        <overrideInternetFlag>false</overrideInternetFlag>
      </flags>
    </filerInfo>
  </headerData>
  <formData>
    <submissionInformation>
      <periodBegin>04-01-2021</periodBegin>
      <periodEnd>03-31-2022</periodEnd>
      <typeOfRegistrant>
        <typeOfBDRegistrant>Broker-dealer</typeOfBDRegistrant>
      </typeOfRegistrant>
      <materialWeakness>N</materialWeakness>
    </submissionInformation>
    <registrantIdentification>
      <brokerDealerName>CANACCORD GENUITY WEALTH MANAGEMENT (USA) INC.</brokerDealerName>
      <businessAddress>
        <com:street1>609 GRANVILLE ST.</com:street1>
        <com:street2>SUITE 2200</com:street2>
        <com:city>VANCOUVER</com:city>
        <com:stateOrCountry>A1</com:stateOrCountry>
        <com:zipCode>V7Y 1H2</com:zipCode>
      </businessAddress>
      <contactPersonName>Don MacFayden</contactPersonName>
      <contactPersonPhoneNumber>2123898088</contactPersonPhoneNumber>
    </registrantIdentification>
    <accountantIdentification>
      <accountantName>Ernst &amp; Young</accountantName>
      <accountantAddress>
        <com:street1>Oceanic Plaza 1066 W. Hastings St</com:street1>
        <com:street2>Suite 2300</com:street2>
        <com:city>Vancouver</com:city>
        <com:stateOrCountry>A1</com:stateOrCountry>
        <com:zipCode>V6E 3X2</com:zipCode>
      </accountantAddress>
      <accountantType>Certified Public Accountant not resident in United States or any of its possessions</accountantType>
    </accountantIdentification>
    <oathSignature>
      <signPersonName>Donald D. Macfayden</signPersonName>
      <entityName>CANACCORD GENUITY WEALTH MANAGEMENT (USA) INC.</entityName>
      <signDate>03-31-2022</signDate>
      <signature>Donald Macfayden</signature>
      <oathTitle>CFO</oathTitle>
      <confirmNotarizedFlag>Y</confirmNotarizedFlag>
    </oathSignature>
  </formData>
</edgarSubmission>
