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    <nameOfIssuer>ALECTOR INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>014442107</cusip>
    <value>1809000</value>
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    <votingAuthority>
      <Sole>900000</Sole>
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    <nameOfIssuer>ALUMIS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>022307102</cusip>
    <value>3658200</value>
    <shrsOrPrnAmt>
      <sshPrnamt>130000</sshPrnamt>
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      <Sole>130000</Sole>
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    <nameOfIssuer>AMYLYX PHARMACEUTICALS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>03237H101</cusip>
    <value>2011520</value>
    <shrsOrPrnAmt>
      <sshPrnamt>112000</sshPrnamt>
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    <votingAuthority>
      <Sole>112000</Sole>
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    <nameOfIssuer>BEAM THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>07373V105</cusip>
    <value>16347920</value>
    <shrsOrPrnAmt>
      <sshPrnamt>476338</sshPrnamt>
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      <Sole>476338</Sole>
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    <nameOfIssuer>BIOCRYST PHARMACEUTICALS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>09058V103</cusip>
    <value>5200000</value>
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      <sshPrnamt>520000</sshPrnamt>
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    <votingAuthority>
      <Sole>520000</Sole>
      <Shared>0</Shared>
      <None>0</None>
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    <nameOfIssuer>BIOMARIN PHARMACEUTICAL INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>09061G101</cusip>
    <value>2689340</value>
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      <Sole>47000</Sole>
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      <None>0</None>
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  <infoTable>
    <nameOfIssuer>CELLDEX THERAPEUTICS INC NEW</nameOfIssuer>
    <titleOfClass>COM NEW</titleOfClass>
    <cusip>15117B202</cusip>
    <value>36837900</value>
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      <sshPrnamt>990000</sshPrnamt>
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    <votingAuthority>
      <Sole>990000</Sole>
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      <None>0</None>
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    <nameOfIssuer>COGENT BIOSCIENCES INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>19240Q201</cusip>
    <value>45307638</value>
    <shrsOrPrnAmt>
      <sshPrnamt>1170740</sshPrnamt>
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      <Sole>1170740</Sole>
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      <None>0</None>
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    <nameOfIssuer>CULLINAN THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>230031106</cusip>
    <value>12564900</value>
    <shrsOrPrnAmt>
      <sshPrnamt>690000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>690000</Sole>
      <Shared>0</Shared>
      <None>0</None>
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    <nameOfIssuer>CYTOMX THERAPEUTICS INC.</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>23284F105</cusip>
    <value>17062500</value>
    <shrsOrPrnAmt>
      <sshPrnamt>4550000</sshPrnamt>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>4550000</Sole>
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      <None>0</None>
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  <infoTable>
    <nameOfIssuer>DBV TECHNOLOGIES S A</nameOfIssuer>
    <titleOfClass>SPONSORED ADS</titleOfClass>
    <cusip>23306J309</cusip>
    <value>4346000</value>
    <shrsOrPrnAmt>
      <sshPrnamt>265000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>265000</Sole>
      <Shared>0</Shared>
      <None>0</None>
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    <nameOfIssuer>DESIGN THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>25056L103</cusip>
    <value>1561313</value>
    <shrsOrPrnAmt>
      <sshPrnamt>107900</sshPrnamt>
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      <Sole>107900</Sole>
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      <None>0</None>
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    <nameOfIssuer>ENGENE THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>29286X101</cusip>
    <value>363300</value>
    <shrsOrPrnAmt>
      <sshPrnamt>210000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>210000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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    <nameOfIssuer>IMMUNOCORE HLDGS PLC</nameOfIssuer>
    <titleOfClass>ADS</titleOfClass>
    <cusip>45258D105</cusip>
    <value>2576290</value>
    <shrsOrPrnAmt>
      <sshPrnamt>81143</sshPrnamt>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>81143</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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    <nameOfIssuer>INSMED INC</nameOfIssuer>
    <titleOfClass>COM PAR $.01</titleOfClass>
    <cusip>457669307</cusip>
    <value>6930300</value>
    <shrsOrPrnAmt>
      <sshPrnamt>65000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>65000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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    <nameOfIssuer>KRYSTAL BIOTECH INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>501147102</cusip>
    <value>8176740</value>
    <shrsOrPrnAmt>
      <sshPrnamt>22000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>22000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>LEGEND BIOTECH CORP</nameOfIssuer>
    <titleOfClass>SPONSORED ADS</titleOfClass>
    <cusip>52490G102</cusip>
    <value>16478033</value>
    <shrsOrPrnAmt>
      <sshPrnamt>570569</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>570569</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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  <infoTable>
    <nameOfIssuer>MBX BIOSCIENCES INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>55287L101</cusip>
    <value>5023200</value>
    <shrsOrPrnAmt>
      <sshPrnamt>91000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>91000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>NURIX THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>67080M103</cusip>
    <value>11159600</value>
    <shrsOrPrnAmt>
      <sshPrnamt>460000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>460000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>PHARVARIS N V</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>N69605108</cusip>
    <value>18180435</value>
    <shrsOrPrnAmt>
      <sshPrnamt>525750</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
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      <Sole>525750</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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  <infoTable>
    <nameOfIssuer>PROTAGONIST THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>74366E102</cusip>
    <value>4658040</value>
    <shrsOrPrnAmt>
      <sshPrnamt>38000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>38000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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    <nameOfIssuer>RELAY THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>75943R102</cusip>
    <value>27415370</value>
    <shrsOrPrnAmt>
      <sshPrnamt>1465279</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>1465279</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>SEPTERNA INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>81734D104</cusip>
    <value>1655880</value>
    <shrsOrPrnAmt>
      <sshPrnamt>49444</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>49444</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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    <nameOfIssuer>SUMMIT THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>86627T108</cusip>
    <value>7194957</value>
    <shrsOrPrnAmt>
      <sshPrnamt>493820</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>493820</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>SUPERNUS PHARMACEUTICALS</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>868459108</cusip>
    <value>3255700</value>
    <shrsOrPrnAmt>
      <sshPrnamt>70000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>70000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>SUTRO BIOPHARMA INC</nameOfIssuer>
    <titleOfClass>COM SHS</titleOfClass>
    <cusip>869367201</cusip>
    <value>1063628</value>
    <shrsOrPrnAmt>
      <sshPrnamt>32037</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>32037</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>SYNDAX PHARMACEUTICALS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>87164F105</cusip>
    <value>40550300</value>
    <shrsOrPrnAmt>
      <sshPrnamt>1855000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>1855000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>TRAVERE THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>89422G107</cusip>
    <value>16622606</value>
    <shrsOrPrnAmt>
      <sshPrnamt>292600</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>292600</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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  <infoTable>
    <nameOfIssuer>TYRA BIOSCIENCES INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>90240B106</cusip>
    <value>638800</value>
    <shrsOrPrnAmt>
      <sshPrnamt>20000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>20000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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  <infoTable>
    <nameOfIssuer>UNITED THERAPEUTICS CORP DEL</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>91307C102</cusip>
    <value>8127450</value>
    <shrsOrPrnAmt>
      <sshPrnamt>15000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>15000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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  <infoTable>
    <nameOfIssuer>UROGEN PHARMA LTD</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>M96088105</cusip>
    <value>4416000</value>
    <shrsOrPrnAmt>
      <sshPrnamt>120000</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>120000</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
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  <infoTable>
    <nameOfIssuer>VAXCYTE INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>92243G108</cusip>
    <value>26294524</value>
    <shrsOrPrnAmt>
      <sshPrnamt>452340</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>452340</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>VERA THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>CL A</titleOfClass>
    <cusip>92337R101</cusip>
    <value>18730987</value>
    <shrsOrPrnAmt>
      <sshPrnamt>436518</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
    </shrsOrPrnAmt>
    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>436518</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>VIRIDIAN THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>92790C104</cusip>
    <value>18093182</value>
    <shrsOrPrnAmt>
      <sshPrnamt>984931</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>984931</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
  <infoTable>
    <nameOfIssuer>WAVE LIFE SCIENCES LTD</nameOfIssuer>
    <titleOfClass>SHS</titleOfClass>
    <cusip>Y95308105</cusip>
    <value>1033285</value>
    <shrsOrPrnAmt>
      <sshPrnamt>177846</sshPrnamt>
      <sshPrnamtType>SH</sshPrnamtType>
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    <investmentDiscretion>SOLE</investmentDiscretion>
    <votingAuthority>
      <Sole>177846</Sole>
      <Shared>0</Shared>
      <None>0</None>
    </votingAuthority>
  </infoTable>
</informationTable>
