0002050194-26-000004.txt : 20260514 0002050194-26-000004.hdr.sgml : 20260514 20260514163723 ACCESSION NUMBER: 0002050194-26-000004 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20260331 FILED AS OF DATE: 20260514 DATE AS OF CHANGE: 20260514 EFFECTIVENESS DATE: 20260514 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Spruce Street Capital LP CENTRAL INDEX KEY: 0002050194 ORGANIZATION NAME: EIN: 991180831 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-26325 FILM NUMBER: 26979769 BUSINESS ADDRESS: STREET 1: 777 THIRD AVENUE STREET 2: SUITE 1704 CITY: NEW YORK STATE: NY ZIP: 10017 BUSINESS PHONE: (646) 416-9712 MAIL ADDRESS: STREET 1: 777 THIRD AVENUE STREET 2: SUITE 1704 CITY: NEW YORK STATE: NY ZIP: 10017 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0002050194 XXXXXXXX 03-31-2026 03-31-2026 Spruce Street Capital LP

777 THIRD AVENUE SUITE 1704 NEW YORK NY 10017

13F HOLDINGS REPORT 028-26325 000333213 801-132577 N Stephen Leslie Cohen 6464169712 Stephen Leslie Cohen New York NY 05-14-2026 0 28 415936109 false INFORMATION TABLE 2 sprucestreetq1202613f.xml ALECTOR INC COM 014442107 4517296 2101068 SH SOLE 2101068 0 0 ALKERMES PLC SHS G01767105 11244197 317992 SH SOLE 317992 0 0 ALUMIS INC COM 022307102 8648405 392574 SH SOLE 392574 0 0 ALTO NEUROSCIENCE INC COM SHS 02157Q109 29116321 1325210 SH SOLE 1325210 0 0 AN2 THERAPEUTICS INC COM 037326105 5575870 1661073 SH SOLE 1661073 0 0 CENTESSA PHARMACEUTICALS SPONSORED ADS 152309100 19456802 489849 SH SOLE 489849 0 0 CENTURY THERAPEUTICS COM 15673T100 9173462 4059054 SH SOLE 4059054 0 0 CORVUS PHARMACEUTICALS I COM 221015100 3388089 231585 SH SOLE 231585 0 0 DIANTHUS THERAPEUTICS IN COM 252828108 31325154 373274 SH SOLE 373274 0 0 ENANTA PHARMACEUTICALS I COM 29251M106 11778713 932598 SH SOLE 932598 0 0 ENLIVEN THERAPEUTICS INC COM 29337E102 12897035 329006 SH SOLE 329006 0 0 ERASCA INC COM 29479A108 6836746 422543 SH SOLE 422543 0 0 HELIX ACQUISITION CORP III USD CL A ORD SHS G4444S107 5080000 500000 SH SOLE 500000 0 0 INHIBIKASE THERAPEUTI COM NEW 45719W205 6017093 3581603 SH SOLE 3581603 0 0 KALVISTA PHARMACEUTICALS COM 483497103 18070319 897681 SH SOLE 897681 0 0 KINIKSA PHARMACEUTICALS I ORD SHS CL A G52694109 36645183 761063 SH SOLE 761063 0 0 LB PHARMACEUTICALS INC COM SHS 50180M108 33644866 1376159 SH SOLE 1376159 0 0 LEONABIO INC COM 04746L203 3844884 393701 SH SOLE 393701 0 0 LEXEO THERAPEUTICS INC COM 52886X107 5330124 928593 SH SOLE 928593 0 0 MAZE THERAPEUTICS INC COM 578784100 5970000 200000 SH SOLE 200000 0 0 MINERVA NEUROSCIENC COM NEW 603380205 9974388 1655500 SH SOLE 1655500 0 0 PERSPECTIVE THERAPEUTICS COM NEW 46489V302 10955036 2627107 SH SOLE 2627107 0 0 RELAY THERAPEUTICS INC COM 75943R102 29692044 2984125 SH SOLE 2984125 0 0 RELMADA THERAPEUTICS INC COM 75955J402 42998208 6262114 SH SOLE 6262114 0 0 SAB BIOTHERAPEUTICS IN COM NEW 78397T202 8420263 2198502 SH SOLE 2198502 0 0 SAVARA INC COM 805111101 18472136 3383175 SH SOLE 3383175 0 0 SURROZEN INC COM NEW COM NEW 86889P208 12585325 432040 SH SOLE 432040 0 0 VAXCYTE INC COM 92243G108 14278150 245709 SH SOLE 245709 0 0