X0306 5 2021-12-31 0 0 0000203596 WESBANCO INC WSBC 0001197905 TANNER REED J C/O WESBANCO, INC. ONE BANK PLAZA WHEELING WV 26003 1 Common Stock 7191.86 D Common Stock 7440.215 I By Trust Deferred Common Stock 2622 I Co-ttee Family Trust Depositary Shares 1000 D Depositary Shares 2000 I By IRA Depositary Shares 1000 I By Spouse Depositary Shares 2000 I By Spouse IRA Phantom Stock Common Stock 20289.335 20289.335 D Includes 251.746 shares acquired from the WesBanco, Inc. Dividend Reinvestment Plan. Includes 276.65 additional shares acquired from the WesBanco, Inc. Dividend Reinvestment Plan allocated pursuant to participation in the WesBanco Directors Deferred Compensation Plan. Under the terms of the Plan, shares are held in a Rabbi Trust. Each share of phantom stock is the economic equivalent of one share of WesBanco, Inc. common stock and were acquired through reporting person's participation in the WesBanco Deferred Compensation Plan. Includes 747.98 additional shares acquired from the WesBanco, Inc. Dividend Reinvestment Plan, allocated pursuant to participation in the WesBanco Deferred Compensation Plan. /s/ Daniel K. Weiss, Attorney-in-Fact 2022-02-11