X0306 5 2020-12-31 0 0 0000203596 WESBANCO INC WSBC 0001640558 Zatta Jayson M C/O WESBANCO INC ONE BANK PLAZA WHEELING WV 26003 1 SR EVP & Chief Banking Officer Common Stock 37722.586 D Common Stock 2028.944 I By KSOP Depositary Shares 2000 D Stock Option 28.79 2021-05-21 Common Stock 1500 1500 D Stock Option 21.55 2027-05-27 Common Stock 2250 2250 D Stock Option 31.58 2022-06-02 Common Stock 2000 2000 D Stock Option 32.37 2023-05-25 Common Stock 2250 2250 D Stock Option 38.88 2024-05-16 Common Stock 2250 2250 D Stock Option 45.65 2025-05-16 Common Stock 2250 2250 D Stock Option 38.93 2026-05-15 Common Stock 2250 2250 D Includes 720.423 shares acquired from the WesBanco, Inc. Dividend Reinvestment Plan. Includes 297.812 shares credited to reporting person's KSOP account. Options vested in 2 equal installments beginning 12/31/14. Options vest in 2 equal installments beginning 12/31/20. Options vested in equal installments beginning 12/31/2015. Options vested in 2 equal installments beginning 12/31/16. Options vested in 2 equal installments beginning 12/31/17. Options vested in 2 equal installments beginning 12/31/18. Options vested in 2 equal installments beginning 12/31/19. /s/ Robert H. Young, Attorney-in-Fact 2021-02-16