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Significant Agreements (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 18, 2024
Dec. 31, 2022
Jun. 30, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Refundable deposit amount $ 1,900 $ 1,900      
Total operating expenses 155,604 82,389      
IQVIA RDS Inc | Master Clinical Contract Services Agreement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Initial payment amount     $ 12,800   $ 1,800
Total operating expenses 37,500 15,100      
Amount paid 31,200 15,500      
Accounts payable 400 500      
Accrued expenses and other current liabilities $ 8,600 $ 6,000      
IQVIA RDS Inc | Master Clinical Contract Services Agreement, Refundable Deposit          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Initial payment amount         1,000
IQVIA RDS Inc | Master Clinical Services Agreement, Investigator Grant Payment          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Initial payment amount     7,300   $ 800
IQVIA RDS Inc | Master Clinical Contract Services Agreement, Additional Refundable Deposit          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Initial payment amount       $ 900  
IQVIA RDS Inc | Master Clinical Contract Services Agreement, Deposits For Services          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Initial payment amount     4,500    
IQVIA RDS Inc | Master Clinical Contract Services Agreement, Deposits For Pass Through Costs          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Initial payment amount     $ 1,000    
IQVIA RDS Inc | Master Clinical Contract Services Agreement, Incremental Return          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Commitments (as a percent)     75.00%