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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Schedule of Provision for Income Taxes
The summary of income tax expense for the year ended December 31, 2025 is as follows (in thousands):

2025
Current income taxes
Federal$— 
State217 
Total current income taxes217 
Deferred income taxes
Federal — 
State— 
Total deferred income taxes— 
Total tax expense$217 
Federal— 
State217 

As previously disclosed for the year ended December 31, 2024, prior to the adoption of ASU 2023-09, the summary of the income tax expense for the year ended December 31, 2024 is as follows:

2024
Current income taxes
Federal$— 
State187 
Total current income taxes187 
Deferred income taxes
Federal — 
State— 
Total deferred income taxes— 
Total tax expense$187 
Schedule of Effective Income Tax Rate Reconciliation
The following table presents a reconciliation of expected income tax (expense) benefit for the year ended December 31, 2025:
As of December 31, 2025
RateTax
At U.S. federal statutory rate21.00 %(28,924)
State taxes, net of federal effect(1)
(0.12)%165 
Tax credits
      Research and Development credit2.45 %(3,377)
Changes in valuation allowances(22.86)%31,487 
Nontaxable or nondeductible items
    Stock compensation(0.52)%712 
    Other Nontaxable or nondeductible items(0.04)%59 
Other Adjustments
   Other items(0.06)%95 
Effective income tax rate(0.15)%217 

(1) In 2025, state and local income taxes in Massachusetts (98)% comprise the majority of the state and local income taxes category.

As previously disclosed for the year ended December 31, 2024, prior to adoption of ASU 2023-09, the following table presents a reconciliation of expected income tax (expense) benefit for the year ended December 31, 2024:

As of December 31,
2024
Income tax computed at federal statutory tax rate21.0 %
State taxes, net of federal benefit6.7 %
Change in valuation allowance(31.3)%
General business credit carryovers4.1 %
Permanent differences(0.5)%
Other0.1 %
Total— %
Schedule of Deferred Income Tax Assets (Liabilities)
The significant components of the Company's deferred income tax assets (liabilities) are as follows (dollars in thousands):

As of December 31,
20252024
Deferred tax assets
Net operating losses52,044 25,269 
Tax credit carryforwards8,283 4,570 
Intangibles1,367 1,528 
Startup costs, depreciation and other20 10 
Capitalized R&D (Section 174)31,983 26,292 
Stock compensation4,077 1,335 
Lease liability529 195 
Total gross deferred tax asset98,303 59,199 
Deferred tax liabilities - ROU asset(522)(182)
Valuation allowance(97,781)(59,017)
Net deferred tax asset— —