<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Pontifax Management 4 G.P. (2015) Ltd. -->
          <cik>0001726334</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Shares, no nominal value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>03/31/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0002020932</issuerCik>
        <issuerName>Agomab Therapeutics NV</issuerName>
        <issuerCusips>
          <issuerCusipNumber>00860C102</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>Posthoflei 1/6</com:street1>
          <com:city>Antwerpen</com:city>
          <com:stateOrCountry>C9</com:stateOrCountry>
          <com:zipCode>2600</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Pontifax VI G.P. L.P.</reportingPersonName>
      <citizenshipOrOrganization>L3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3305846.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3305846.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3305846.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>6.8</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
      <comments>Consists of (a) 1,759,574 shares held by Pontifax (Israel) V, L.P., (b) 469,982 shares held by Pontifax (Cayman) V, L.P, (c) 683,616 shares held by Pontifax (China) V L.P.; and (d) 392,674 shares held by Pontifax Late Stage L.P. (collectively, the "Pontifax Entities"). Pontifax VI G.P. L.P. ("Pontifax VI GP") is the general partner of each of the Pontifax Entities. Pontifax Management 4 G.P. (2015) Ltd. ("Pontifax Management") is the general partner of Pontifax VI GP. Mr. Tomer Kariv and Mr. Ran Nussbaum are the directors of Pontifax Management. Each of Mr. Kariv and Mr. Nussbaum disclaim beneficial ownership of the shares held by the Pontifax Entities and the inclusion of such shares in this Schedule 13G shall not be deemed to be an admission of beneficial ownership of the reported shares.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Pontifax Management 4 G.P. (2015) Ltd.</reportingPersonName>
      <citizenshipOrOrganization>L3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3305846.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3305846.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3305846.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>6.8</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
      <comments>Consists of (a) 1,759,574 shares held by Pontifax (Israel) V, L.P., (b) 469,982 shares held by Pontifax (Cayman) V, L.P, (c) 683,616 shares held by Pontifax (China) V L.P.; and (d) 392,674 shares held by Pontifax Late Stage L.P. Pontifax VI GP is the general partner of each of the Pontifax Entities. Pontifax Management is the general partner of Pontifax VI GP. Mr. Tomer Kariv and Mr. Ran Nussbaum are the directors of Pontifax Management. Each of Mr. Kariv and Mr. Nussbaum disclaim beneficial ownership of the shares held by the Pontifax Entities and the inclusion of such shares in this Schedule 13G shall not be deemed to be an admission of beneficial ownership of the reported shares.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Ran Nussbaum</reportingPersonName>
      <citizenshipOrOrganization>L3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3305846.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3305846.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3305846.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>6.8</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Consists of (a) 1,759,574 shares held by Pontifax (Israel) V, L.P., (b) 469,982 shares held by Pontifax (Cayman) V, L.P, (c) 683,616 shares held by Pontifax (China) V L.P.; and (d) 392,674 shares held by Pontifax Late Stage L.P. Pontifax VI GP is the general partner of each of the Pontifax Entities. Pontifax Management is the general partner of Pontifax VI GP. Mr. Tomer Kariv and Mr. Ran Nussbaum are the directors of Pontifax Management. Each of Mr. Kariv and Mr. Nussbaum disclaim beneficial ownership of the shares held by the Pontifax Entities and the inclusion of such shares in this Schedule 13G shall not be deemed to be an admission of beneficial ownership of the reported shares.</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Tomer Kariv</reportingPersonName>
      <citizenshipOrOrganization>L3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3305846.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3305846.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3305846.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>6.8</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Consists of (a) 1,759,574 shares held by Pontifax (Israel) V, L.P., (b) 469,982 shares held by Pontifax (Cayman) V, L.P, (c) 683,616 shares held by Pontifax (China) V L.P.; and (d) 392,674 shares held by Pontifax Late Stage L.P. Pontifax VI GP is the general partner of each of the Pontifax Entities. Pontifax Management is the general partner of Pontifax VI GP. Mr. Tomer Kariv and Mr. Ran Nussbaum are the directors of Pontifax Management. Each of Mr. Kariv and Mr. Nussbaum disclaim beneficial ownership of the shares held by the Pontifax Entities and the inclusion of such shares in this Schedule 13G shall not be deemed to be an admission of beneficial ownership of the reported shares.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Agomab Therapeutics NV</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>Posthoflei 1/6, Antwerpen, Belgium, 2600</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>This Statement is filed on behalf of Pontifax VI G.P. L.P., Pontifax Management 4 G.P. (2015) Ltd., Ran Nussbaum and Tomer Kariv.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>The addresses of the Reporting Persons are:
Pontifax VI G.P. L.P. - 14 Shenkar St. Herzliya, 46140, Israel
Pontifax Management 4 G.P. (2015) Ltd. - 14 Shenkar St. Herzliya, 46140, Israel
Ran Nussbaum - 14 Shenkar St. Herzliya, 46140, Israel
Tomer Kariv - 14 Shenkar St. Herzliya, 46140, Israel</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Pontifax VI G.P. L.P. is organized in the State of Israel, Pontifax Management 4 G.P. (2015) Ltd. is incorporated in the State of Israel, and Ran Nussbaum and Tomer Kariv are citizens of the State of Israel.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>3,305,846</amountBeneficiallyOwned>
        <classPercent>6.8%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>3,305,846</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>3,305,846</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>Y</notApplicableFlag>
      </item10>
    </items>
    <exhibitInfo>A. Joint Filing Agreement, dated as of April 16, 2026, by and among Pontifax VI G.P. L.P., Pontifax Management 4 G.P. (2015) Ltd., Ran Nussbaum and Tomer Kariv.</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>Pontifax VI G.P. L.P.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Pontifax Management 4 G.P. (2015) Ltd.</signature>
        <title>Pontifax Management 4 G.P. (2015) Ltd./General Partner</title>
        <date>04/16/2026</date>
      </signatureDetails>
      <signatureDetails>
        <signature>/s/ Ran Nussbaum</signature>
        <title>Ran Nussbaum/Director</title>
        <date>04/16/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Pontifax Management 4 G.P. (2015) Ltd.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Ran Nussbaum</signature>
        <title>Ran Nussbaum/Director</title>
        <date>04/16/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Ran Nussbaum</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Ran Nussbaum</signature>
        <title>Ran Nussbaum</title>
        <date>04/16/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Tomer Kariv</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Tomer Kariv</signature>
        <title>Tomer Kariv</title>
        <date>04/16/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
