Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components - Schedule of Property and Equipment, Net (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 304,150	$ 296,426
Less: accumulated depreciation and amortization	(240,980)	(228,609)
Property and equipment, net	63,170	67,817
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property and equipment	76,430	73,312
Capitalized software
Property, Plant and Equipment [Line Items]
Total property and equipment	27,898	25,921
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total property and equipment	106,227	103,795
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Total property and equipment	8,368	9,110
Leasehold improvements/Leased buildings
Property, Plant and Equipment [Line Items]
Total property and equipment	63,812	63,039
Aircraft and leased equipment
Property, Plant and Equipment [Line Items]
Total property and equipment	$ 21,415	$ 21,249