Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components (Tables)

9 Months Ended

Sep. 30, 2025

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure

Prepaid expenses and other current assets consist of the following:

	As of September 30, 2025		As of December 31, 2024
	(amounts in thousands)
Prepaid expenses	$	18,657	$	13,562
Other current assets	2,577		6,708
Total prepaid expenses and other current assets	$	21,234	$	20,270

Schedule of Property, Plant and Equipment

Depreciation and amortization expenses are calculated on a straight-line basis and applied to asset classes based upon the Company’s estimate of the asset class’s useful life, as summarized below:

	Estimated Useful Life
Laboratory equipment	3 years
Computer equipment and software	3 years
Furniture and fixtures	5 years
Aircraft	15 years
Leasehold improvements/leased buildings	Lesser of remaining lease term or useful life
Leased equipment	Lesser of initial lease term or 5 years

Property and equipment, net consist of the following:

	As of September 30, 2025		As of December 31, 2024
	(amounts in thousands)
Computer equipment and software	$	75,814	$	73,312
Capitalized software	27,097		25,921
Laboratory equipment	108,476		103,795
Furniture and fixtures	8,305		9,110
Leasehold improvements/Leased buildings	63,502		63,039
Aircraft and leased equipment	21,255		21,249
Total property and equipment	304,449		296,426
Less: accumulated depreciation and amortization	(240,452)		(228,609)
Property and equipment, net	$	63,997	$	67,817

Schedule of Accrued Liabilities

Accrued expenses and other current liabilities consist of the following:

	As of September 30, 2025		As of December 31, 2024
	(amounts in thousands)
Trade accruals	$	5,635	$	7,131
Accrued payroll and employee medical	14,270		17,882
Accrued bonus	20,905		25,736
Current portion of early exercise stock option liability	327		4,957
Contract liability	2,791		7,470
Current portion of operating lease liabilities	6,450		6,080
Other accrued expenses	6,489		8,286
Total accrued expenses and other current liabilities	$	56,867	$	77,542

Schedule of Other Long-Term Liabilities

Other long-term liabilities consist of the following:

	As of September 30, 2025		As of December 31, 2024
	(amounts in thousands)
Long-term operating lease liabilities, net of current portion	$	43,828	$	38,651
Long-term portion of early exercise stock option liability	53		5,767
Total other long-term liabilities	$	43,881	$	44,418

Schedule of Other Income (Expense), Net

Other income (expense), net, consists of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2025		2024		2025		2024
	(amounts in thousands)
Loss on debt extinguishment	$	—	$	—	$	(17,930)	$	—
Other	(89)		37		(517)		(323)
Total other income (expense), net	$	(89)	$	37	$	(18,447)	$	(323)