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Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components
6 Months Ended
Jun. 30, 2025
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components Condensed Consolidated Balance Sheet and Statement of Operations and Comprehensive Loss Components
Prepaid Expenses and Other Current Assets
Prepaid expenses and other current assets consist of the following:
As of June 30, 2025As of December 31, 2024
(amounts in thousands)
Prepaid expenses$16,575 $13,562 
Other current assets2,549 6,708 
Total prepaid expenses and other current assets$19,124 $20,270 
Property and Equipment, Net
Property and equipment, net consist of the following:
As of June 30, 2025As of December 31, 2024
(amounts in thousands)
Computer equipment and software$74,791 $73,312 
Capitalized software26,312 25,921 
Laboratory equipment108,576 103,795 
Furniture and fixtures9,129 9,110 
Leasehold improvements/Leased buildings63,295 63,039 
Aircraft and leased equipment21,249 21,249 
Total property and equipment303,352 296,426 
Less: accumulated depreciation and amortization(242,037)(228,609)
Property and equipment, net$61,315 $67,817 
Total depreciation and amortization expense was $6.4 million and $11.6 million for the three months ended June 30, 2025 and 2024, respectively, and $13.5 million and $29.3 million for the six months ended June 30, 2025 and 2024, respectively.
Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities consist of the following:
As of June 30, 2025As of December 31, 2024
(amounts in thousands)
Trade accruals$5,749 $7,131 
Accrued payroll and employee medical18,308 17,882 
Accrued bonus13,516 25,736 
Current portion of early exercise stock option liability327 4,957 
Contract liability5,340 7,470 
Current portion of operating lease liabilities7,291 6,080 
Other accrued expenses10,826 8,286 
Total accrued expenses and other current liabilities$61,357 $77,542 
Other Long-Term Liabilities
Other long-term liabilities consist of the following:
As of June 30, 2025As of December 31, 2024
(amounts in thousands)
Long-term operating lease liabilities, net of current portion $37,983 $38,651 
Long-term portion of early exercise stock option liability380 5,767 
Total other long-term liabilities$38,363 $44,418 
Other Expense, Net
Other expense, net, consists of the following:
Three Months Ended June 30,Six Months Ended June 30,
2025202420252024
(amounts in thousands)
Loss on debt extinguishment$(17,930)$— $(17,930)$— 
Other(411)(141)(428)(360)
Total other expense, net$(18,341)$(141)$(18,358)$(360)