ABIVAX SA SPONSORED ADS 00370M103 22270000 200000 SH SOLE 200000 0 0 ALLOGENE THERAPEUTICS INC COM 019770106 6649000 2725000 SH SOLE 2725000 0 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 11120000 800000 SH SOLE 800000 0 0 AN2 THERAPEUTICS INC COM 037326105 2561700 749035 SH SOLE 749035 0 0 APOGEE THERAPEUTICS INC COM 03770N101 5891900 70000 SH SOLE 70000 0 0 AVALO THERAPEUTICS INC COM NEW 05338F306 4479000 300000 SH SOLE 300000 0 0 CAPRICOR THERAPEUTICS INC COM NEW 14070B309 17936000 590000 SH SOLE 590000 0 0 CELCUITY INC COM 15102K100 25681500 225000 SH SOLE 225000 0 0 CLENE INC COM NEW 185634201 2354149 477515 SH SOLE 477515 0 0 COGENT BIOSCIENCES INC COM 19240Q201 8660250 225000 SH SOLE 225000 0 0 CONTINEUM THERAPEUTICS INC CL A 21217B100 6451640 494000 SH SOLE 494000 0 0 CORCEPT THERAPEUTICS INC COM 218352102 10077500 250000 SH SOLE 250000 0 0 CORVUS PHARMACEUTICALS INC COM 221015100 16093000 1100000 SH SOLE 1100000 0 0 CRESCENT BIOPHARMA INC. COM 38000Q201 8334212 453686 SH SOLE 453686 0 0 CYBIN INC COM NEW 23256X407 3072000 640000 SH SOLE 640000 0 0 CYTOKINETICS INC COM NEW 23282W605 6591000 100000 SH SOLE 100000 0 0 DEFINIUM THERAPEUTICS INC COM SHS 24477V105 11311650 598500 SH SOLE 598500 0 0 INOVIO PHARMACEUTICALS INC COM SHS 45773H409 4124012 2370122 SH SOLE 2370122 0 0 INVIVYD INC COM 00534A102 1950000 1500000 SH SOLE 1500000 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 410652 20400 SH SOLE 20400 0 0 KARYOPHARM THERAPEUTICS INC COM NEW 48576U205 1685126 302536 SH SOLE 302536 0 0 KODIAK SCIENCES INC COM 50015M109 51881320 1361000 SH SOLE 1361000 0 0 KYMERA THERAPEUTICS INC COM 501575104 27410739 329100 SH SOLE 329100 0 0 LB PHARMACEUTICALS INC COM SHS 50180M108 1726200 70000 SH SOLE 70000 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 793333 666666 SH SOLE 666666 0 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 5126000 275000 SH SOLE 275000 0 0 NURIX THERAPEUTICS INC COM 67080M103 1550000 100000 SH SOLE 100000 0 0 OCULAR THERAPEUTIX INC COM 67576A100 2964500 350000 SH SOLE 350000 0 0 OPUS GENETICS INC COM 67577R102 10237500 2250000 SH SOLE 2250000 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 2236255 176500 SH SOLE 176500 0 0 PALISADE BIO INC COM 696389402 8399781 4799875 SH SOLE 4799875 0 0 PEPGEN INC COM 713317105 483019 272892 SH SOLE 272892 0 0 PRAXIS PRECISION MEDICINES I COM NEW 74006W207 14967981 46457 SH SOLE 46457 0 0 PRECIGEN INC COM 74017N105 13545000 3500000 SH SOLE 3500000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 17918000 170000 SH SOLE 170000 0 0 PTC THERAPEUTICS INC COM 69366J200 13626000 200000 SH SOLE 200000 0 0 REGENXBIO INC COM 75901B107 125700 15000 SH SOLE 15000 0 0 RELMADA THERAPEUTICS INC COM 75955J402 5861058 842106 SH SOLE 842106 0 0 REPLIMUNE GROUP INC COM 76029N106 8988750 1175000 SH SOLE 1175000 0 0 REVOLUTION MEDICINES INC COM 76155X100 48625000 500000 SH SOLE 500000 0 0 SAREPTA THERAPEUTICS INC COM 803607100 3264000 150000 SH SOLE 150000 0 0 SOLENO THERAPEUTICS INC COM 834203309 6696000 200000 SH SOLE 200000 0 0 SOLID BIOSCIENCES INC COM NEW 83422E204 2160000 300000 SH SOLE 300000 0 0 STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 3615000 75000 SH SOLE 75000 0 0 SURROZEN INC COM NEW 86889P208 22322843 766318 SH SOLE 766318 0 0 TANGO THERAPEUTICS INC COM 87583X109 227530501 10876219 SH SOLE 10876219 0 0 TERNS PHARMACEUTICALS INC COM 880881107 19770000 375000 SH SOLE 375000 0 0 UNIQURE NV SHS N90064101 10823700 662000 SH SOLE 662000 0 0 UPSTREAM BIO INC COM 91678A107 1350000 150000 SH SOLE 150000 0 0 UROGEN PHARMA LTD COM M96088105 8990000 500000 SH SOLE 500000 0 0 VAXCYTE INC COM 92243G108 18885750 325000 SH SOLE 325000 0 0 VIR BIOTECHNOLOGY INC COM 92764N102 16719360 1866000 SH SOLE 1866000 0 0 ZURA BIO LTD CLASS A ORD SHS G9TY5A101 5355000 900000 SH SOLE 900000 0 0 SURROZEN INC *W EXP 08/01/203 86889P117 1067 66666 SH SOLE 66666 0 0