The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102   2,987,563 2,390,050 SH   DFND 2 0 2,390,050 0
DYNE THERAPEUTICS INC COM 26818M108   182,172,753 6,416,793 SH   DFND 2 0 6,416,793 0
DYNE THERAPEUTICS INC COM 26818M108   40,557,131 1,428,571 SH   DFND   0 1,428,571 0
ENGENE HOLDINGS INC COM 29286M105   98,034,596 5,783,752 SH   DFND 1 0 5,783,752 0
ENGENE HOLDINGS INC W EXP 10/31/2028 29286M113   12,495,974 2,403,072 SH   DFND 1 0 2,403,072 0
ENGENE HOLDINGS INC COM 29286M105   49,056,673 2,894,199 SH   DFND   0 2,894,199 0
ENGENE HOLDINGS INC W EXP 10/31/2028 29286M113   2,470,395 475,076 SH   DFND   0 475,076 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   122,887,056 5,196,070 SH   DFND 1 0 5,196,070 0
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109   156,926,997 6,635,391 SH   DFND 2 0 6,635,391 0
REPLIMUNE GROUP INC COM 76029N106   39,758,888 4,866,449 SH   DFND   0 4,866,449 0