144 0002010692 XXXXXXXX LIVE 0001962738 CASI Pharmaceuticals, INc. 001-41666 1701-1702, CHINA CENTRAL OFFICE TOWER 1 NO. 81 JIANGUO ROAD, CHAOYANG DISTRICT BEIJING F4 100025 86 10-6561 8789 Panacea Innovation Ltd Owner Ordinary Shares Cantor Fitzgerald

110 East 59th Street New York NY 10022

171000 534186.90 13378175 03/15/2024 NASDAQ Ordinary Shares 09/08/2022 Open Market Purchase Open Market Purchase N 371517 09/08/2022 Cash N Panacea Innovation Ltd.

C/O PANACEA VENTURE, NO. 5, LANE 1350 FUXING MIDDLE ROAD SHANGHAI F4 200031

Ordinary Shares 03/05/2024 134000 925940.00 03/15/2024 /s/ James Huang