144 0002010692 XXXXXXXX LIVE 0001962738 CASI Pharmaceuticals, INc. 001-41666 1701-1702, CHINA CENTRAL OFFICE TOWER 1 NO. 81 JIANGUO ROAD, CHAOYANG DISTRICT BEIJING F4 100025 86 10-6561 8789 Panacea Innovation Ltd Owner Ordinary Shares Jeffries & Co.

Metro Center 1 Station Place, 3 North Stamford CT 06902

54000 373140.00 13378175 03/05/2024 NASDAQ Ordinary Shares Cantor Fitzgerald

110 East 59th Street New York NY 10022

80000 552800.00 13378175 03/05/2024 NASDAQ Ordinary Shares 08/19/2022 Open Market Purchase Open Market Purchase N 171116 08/19/2022 Cash Y 03/05/2024 /s/ James Huang