X0508 4 2026-03-05 0001785279 Metagenomi Therapeutics, Inc. MGX 0002009713 Wein Matthew C/O METAGENOMI THERAPEUTICS, INC. 5959 HORTON STREET, 7TH FLOOR EMERYVILLE CA 94608 false true false false See Remarks false Common Stock 2026-03-05 4 S false 482 1.60 D 114549 D These shares of common stock were automatically sold for the purpose of satisfying the Reporting Person's tax withholding obligations upon the vesting of certain restricted stock units granted to the Reporting Person on each of April 1, 2024 and April 1, 2025, and does not represent a volitional trade by the Reporting Person. Title: General Counsel, Compliance Officer and Corporate Secretary /s/ Matthew L. Wein 2026-03-09