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Research and development costs (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Disclosure of products and services [line items]      
Research and development costs $ 171,249 $ 127,930 $ 85,315
Inter-segment R&D      
Disclosure of products and services [line items]      
Research and development costs (3,759) 0 0
Product Development      
Disclosure of products and services [line items]      
Research and development costs 169,195 127,505 84,927
Therapeutics      
Disclosure of products and services [line items]      
Research and development costs 98,039 55,877 31,258
Therapeutics | Phase 3      
Disclosure of products and services [line items]      
Research and development costs 49,209 36,378 17,585
Therapeutics | Phase 2      
Disclosure of products and services [line items]      
Research and development costs 19,332 8,376 7,937
Therapeutics | Early stage clinical candidates      
Disclosure of products and services [line items]      
Research and development costs 16,995 4,914 4,553
Therapeutics | Pre-clinical research and innovation      
Disclosure of products and services [line items]      
Research and development costs 12,503 6,209 1,183
Precision Medicine      
Disclosure of products and services [line items]      
Research and development costs 71,156 71,628 53,669
Precision Medicine | Commercial      
Disclosure of products and services [line items]      
Research and development costs 18,806 7,139 3,883
Precision Medicine | Pre-commercial      
Disclosure of products and services [line items]      
Research and development costs 46,403 61,831 45,117
Precision Medicine | Pre-commercial | Zircaix      
Disclosure of products and services [line items]      
Research and development costs 14,103 2,779  
Precision Medicine | Pre-clinical research and innovation      
Disclosure of products and services [line items]      
Research and development costs 5,947 2,658 4,669
Manufacturing Solutions      
Disclosure of products and services [line items]      
Research and development costs 5,813 425 388
Manufacturing Solutions | Other research and development projects      
Disclosure of products and services [line items]      
Research and development costs $ 5,813 $ 425 $ 388