144 0002006045 XXXXXXXX LIVE 0001822791 Clene Inc 001-39834 6550 South Millrock Drive Suite G50 Salt Lake City UT 84121 8016769695 Symbiosis II LLC Prior Board Member Common Merrill Lynch

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506384 3775481 10333980 12/03/2025 Nasdaq Common 06/20/2023 Open Market Purchase Issuer N 375000 06/20/2023 Cash Common 10/30/2022 Open Market Purchase Issuer N 49504 10/30/2022 Cash Common 05/24/2021 Open Market Purchase Issuer N 25960 05/24/2021 Cash Common 12/30/2020 Open Market Purchase Issuer N 25000 12/30/2020 Cash Common 08/10/2020 Open Market Purchase Issuer N 30920 08/10/2020 Cash Y 12/05/2025 Justin Skoryi