The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Adicet Bio, Inc. | COM | 007002108 | 12,749 | 728,944 | SH | DFND | 1 | 0 | 728,944 | 0 | |
| Aldeyra Therapeutics, Inc. | COM | 01438T106 | 1,579 | 394,834 | SH | DFND | 1 | 0 | 394,834 | 0 | |
| Arrowhead Pharmaceuticals, Inc. | COM | 04280A100 | 216,196 | 3,260,869 | SH | DFND | 1 | 0 | 3,260,869 | 0 | |
| BiomX Inc. | COM | 09090D103 | 3,413 | 2,133,402 | SH | DFND | 1 | 0 | 2,133,402 | 0 | |
| Castlight Health, Inc. | COM CL B | 14862Q100 | 1,249 | 811,295 | SH | DFND | 1 | 0 | 811,295 | 0 | |
| Catalyst Biosciences, Inc. | COM | 14888D208 | 61 | 66,951 | SH | DFND | 1 | 0 | 66,951 | 0 | |
| Cue Health, Inc. | COM | 229790100 | 74,410 | 5,548,864 | SH | DFND | 1 | 0 | 5,548,864 | 0 | |
| CVRx, Inc. | COM | 126638105 | 42,751 | 3,495,575 | SH | DFND | 1 | 0 | 3,495,575 | 0 | |
| Fate Therapeutics, Inc. | COM | 31189P102 | 197,709 | 3,379,064 | SH | DFND | 1 | 0 | 3,379,064 | 0 | |
| Fusion Pharmaceuticals Inc. | COM | 36118A100 | 15,306 | 3,670,516 | SH | DFND | 1 | 0 | 3,670,516 | 0 | |
| Graybug Vision, Inc. | COM | 38942Q103 | 91 | 49,547 | SH | DFND | 1 | 0 | 49,547 | 0 | |
| Legend Biotech Corporation | ADS | 52490G102 | 75,936 | 1,629,173 | SH | DFND | 1 | 0 | 1,629,173 | 0 | |
| MeiraGTx Holdings plc | COM | G59665102 | 68,812 | 2,898,550 | SH | DFND | 1 | 0 | 2,898,550 | 0 | |
| Nano-X Imaging Ltd. | ORD SHS | M70700105 | 2,798 | 192,429 | SH | DFND | 1 | 0 | 192,429 | 0 | |
| PhaseBio Pharmaceuticals, Inc. | COM | 717224109 | 4,194 | 1,607,044 | SH | DFND | 1 | 0 | 1,607,044 | 0 | |
| Point Biopharma Global Inc. | COM | 730541109 | 5,600 | 1,000,000 | SH | DFND | 1 | 0 | 1,000,000 | 0 | |
| Procept BioRobotics Corporation | COM | 74276L105 | 25,472 | 1,018,478 | SH | DFND | 1 | 0 | 1,018,478 | 0 | |
| Protagonist Therapeutics Inc. | COM | 74366E102 | 83,762 | 2,449,183 | SH | DFND | 1 | 0 | 2,449,183 | 0 | |
| Pulmonx Corporation | COM | 745848101 | 181 | 5,639 | SH | DFND | 1 | 0 | 5,639 | 0 | |
| Senseonics Holdings, Inc. | COM | 81727U105 | 146 | 54,621 | SH | DFND | 1 | 0 | 54,621 | 0 | |
| Tracon Pharmaceuticals, Inc. | COM | 89237H209 | 233 | 84,003 | SH | DFND | 1 | 0 | 84,003 | 0 | |
| Vor Biopharma, Inc. | COM | 929033108 | 12,488 | 1,074,658 | SH | DFND | 1 | 0 | 1,074,658 | 0 | |
| Xencor, Inc. | COM | 98401F105 | 30,012 | 748,062 | SH | DFND | 1 | 0 | 748,062 | 0 | |
| SomaLogic, Inc. | COM | 83444K105 | 3,271 | 281,052 | SH | DFND | N/A | 0 | 281,052 | 0 | |