The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Adicet Bio, Inc. COM 007002108   856,509 364,472 SH   DFND 1 0 364,472 0
Aldeyra Therapeutics, Inc. COM 01438T106   979,918 299,669 SH   DFND 1 0 299,669 0
Arrowhead Pharmaceuticals, Inc. COM 04280A100   7,081,303 247,598 SH   DFND 1 0 247,598 0
BiomX Inc. COM 09090D103   865,440 1,923,201 SH   DFND 1 0 1,923,201 0
Clearside Biomedical, Inc. COM 185063104   259,532 169,629 SH   DFND 1 0 169,629 0
CVRx, Inc. COM 126638105   74,723,460 4,103,430 SH   DFND 1 0 4,103,430 0
Fate Therapeutics, Inc. COM 31189P102   24,802,330 3,379,064 SH   DFND 1 0 3,379,064 0
Fusion Pharmaceuticals Inc. COM 36118A100   78,255,401 3,670,516 SH   DFND 1 0 3,670,516 0
Legend Biotech Corporation ADS 52490G102   45,690,129 814,586 SH   DFND 1 0 814,586 0
MeiraGTx Holdings plc COM G59665102   40,311,258 6,641,064 SH   DFND 1 0 6,641,064 0
Nano-X Imaging Ltd. ORD SHS M70700105   1,551,984 158,852 SH   DFND 1 0 158,852 0
Nanobiotix S.A. SPONSORED ADS 63009J107   36,554,242 5,623,816 SH   DFND 1 0 5,623,816 0
Neumora Therapeutics, Inc. COM 640979100   25,429,869 1,849,445 SH   DFND 1 0 1,849,445 0
Procept BioRobotics Corporation COM 74276L105   17,689,345 357,939 SH   DFND 1 0 357,939 0
Protagonist Therapeutics Inc. COM 74366E102   70,854,864 2,449,183 SH   DFND 1 0 2,449,183 0
Senseonics Holdings, Inc. COM 81727U105   29,009 54,621 SH   DFND 1 0 54,621 0
Tracon Pharmaceuticals, Inc. COM 89237H209   36,104 84,003 SH   DFND 1 0 84,003 0
Vor Biopharma, Inc. COM 929033108   2,546,939 1,074,658 SH   DFND 1 0 1,074,658 0
Xencor, Inc. COM 98401F105   16,554,612 748,062 SH   DFND 1 0 748,062 0
Shockwave Medical, Inc. COM 82489T104   54,318,992 166,812 SH   DFND   0 166,812 0
Kenvue Inc. COM 49177J102   3,912,792,143 182,329,550 SH   DFND   0 182,329,550 0
Standard BioTools Inc COM 34385P108   845,431 311,967 SH   DFND   0 311,967 0