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Segments of Business and Geographic Areas - Sales by Segment of Business (Details)
$ in Millions
12 Months Ended
Dec. 29, 2024
USD ($)
segment
Dec. 31, 2023
USD ($)
Jan. 01, 2023
USD ($)
Segment
Segment Reporting Information [Line Items]      
Number of segments 2   3
Sales to Customers $ 88,821 $ 85,159 $ 79,990
% Change 4.30% 6.50%  
Innovative Medicine      
Segment Reporting Information [Line Items]      
Sales to Customers $ 56,964 $ 54,759 52,563
% Change 4.00% 4.20%  
Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 17,828 $ 18,052 16,935
% Change (1.20%) 6.60%  
Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,396 $ 4,418 5,449
% Change (23.10%) (18.90%)  
Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 7,115 $ 7,140 6,893
% Change (0.40%) 3.60%  
Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 20,781 $ 17,661 15,983
% Change 17.70% 10.50%  
Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,282 $ 3,815 3,417
% Change 12.30% 11.60%  
Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,562 $ 3,671 3,887
% Change (3.00%) (5.50%)  
MedTech      
Segment Reporting Information [Line Items]      
Sales to Customers $ 31,857 $ 30,400 27,427
% Change 4.80% 10.80%  
MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 7,707 $ 6,350 4,300
% Change 21.40% 47.70%  
MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,158 $ 8,942 8,587
% Change 2.40% 4.10%  
MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,845 $ 10,037 9,690
% Change (1.90%) 3.60%  
MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,146 $ 5,072 4,849
% Change 1.50% 4.60%  
Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,605 $ 1,839 2,343
% Change (12.80%) (21.50%)  
Simponi/Simponi Aria | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,190 $ 2,197 2,184
% Change (0.30%) 0.60%  
Stelara | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 10,361 $ 10,858 9,723
% Change (4.60%) 11.70%  
Tremfya | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,670 $ 3,147 2,668
% Change 16.60% 17.90%  
Other Immunology | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3 $ 11 17
% Change (74.10%) (33.80%)  
COVID-19 | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 198 $ 1,117 2,179
% Change (82.40%) (48.80%)  
EDURANT/rilpivirine | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,272 $ 1,150 1,008
% Change 10.60% 14.10%  
PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,712 $ 1,854 1,943
% Change (7.70%) (4.60%)  
Other Infectious Diseases | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 214 $ 297 318
% Change (27.60%) (6.70%)  
CONCERTA/Methylphenidate | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 641 $ 783 644
% Change (18.10%) 21.60%  
INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,222 $ 4,115 4,140
% Change 2.60% (0.60%)  
SPRAVATO | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,077 $ 689 374
% Change 56.40% 84.10%  
OTHER NEUROSCIENCE | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,175 $ 1,553 1,734
% Change (24.30%) (10.40%)  
CARVYKTI | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 963 $ 500 133
% Change 92.70%    
DARZALEX | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 11,670 $ 9,744 7,977
% Change 19.80% 22.20%  
ERLEADA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,999 $ 2,387 1,881
% Change 25.60% 26.90%  
IMBRUVICA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,038 $ 3,264 3,784
% Change (6.90%) (13.70%)  
TECVAYLI | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 549 $ 395 15
% Change 38.80%    
ZYTIGA/abiraterone acetate | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 631 $ 887 1,770
% Change (28.80%) (49.90%)  
Other Oncology | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 931 $ 484 423
% Change 92.50% 14.40%  
OPSUMIT | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,184 $ 1,973 1,783
% Change 10.70% 10.60%  
UPTRAVI | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,817 $ 1,582 1,322
% Change 14.90% 19.70%  
Other Pulmonary Hypertension | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 281 $ 260 313
% Change 7.90% (16.70%)  
XARELTO | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,373 $ 2,365 2,473
% Change 0.30% (4.40%)  
Other | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,189 $ 1,306 1,414
% Change (8.90%) (7.60%)  
ELECTROPHYSIOLOGY | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,267 $ 4,688 3,937
% Change 12.30% 19.10%  
Abiomed | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,496 $ 1,306 31
% Change 14.50%    
Shockwave Medical, Inc. | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 564 0 0
other cardiovascular | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 380 $ 356 332
% Change 6.90% 7.10%  
HIPS | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,638 $ 1,560 1,514
% Change 5.00% 3.00%  
KNEES | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,545 $ 1,456 1,359
% Change 6.10% 7.10%  
TRAUMA | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,049 $ 2,979 2,871
% Change 2.30% 3.80%  
SPINE,SPORTS & OTHER | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,926 $ 2,947 2,843
% Change (0.70%) 3.70%  
ADVANCED | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,488 $ 4,671 4,569
% Change (3.90%) 2.20%  
GENERAL | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,358 $ 5,366 5,121
% Change (0.20%) 4.80%  
CONTACT LENSES/OTHER | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,733 $ 3,702 3,543
% Change 0.80% 4.50%  
SURGICAL | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,413 $ 1,370 1,306
% Change 3.20% 4.90%  
United States      
Segment Reporting Information [Line Items]      
Sales to Customers $ 50,302 $ 46,444 41,981
% Change 8.30% 10.60%  
United States | Innovative Medicine      
Segment Reporting Information [Line Items]      
Sales to Customers $ 33,970 $ 31,169 28,604
% Change 9.00% 9.00%  
United States | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 11,355 $ 11,539 11,036
% Change (1.60%) 4.60%  
United States | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,354 $ 1,500 1,680
% Change (9.80%) (10.70%)  
United States | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,398 $ 4,065 3,570
% Change 8.20% 13.90%  
United States | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 10,854 $ 8,462 6,930
% Change 28.30% 22.10%  
United States | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,143 $ 2,697 2,346
% Change 16.50% 15.00%  
United States | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,866 $ 2,906 3,042
% Change (1.40%) (4.50%)  
United States | MedTech      
Segment Reporting Information [Line Items]      
Sales to Customers $ 16,332 $ 15,275 13,377
% Change 6.90% 14.20%  
United States | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,513 $ 3,633 2,169
% Change 24.20% 67.50%  
United States | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,689 $ 5,525 5,321
% Change 3.00% 3.80%  
United States | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,003 $ 4,031 3,897
% Change (0.70%) 3.40%  
United States | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,128 $ 2,086 1,990
% Change 2.00% 4.80%  
United States | Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,009 $ 1,143 1,417
% Change (11.70%) (19.30%)  
United States | Simponi/Simponi Aria | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,082 $ 1,124 1,166
% Change (3.80%) (3.60%)  
United States | Stelara | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,720 $ 6,966 6,388
% Change (3.50%) 9.00%  
United States | Tremfya | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,443 $ 2,147 1,844
% Change 13.70% 16.50%  
United States | Other Immunology | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3 $ 11 17
% Change (74.10%) (33.80%)  
United States | COVID-19 | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 0 $ 0 120
% Change 0.00%    
United States | EDURANT/rilpivirine | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 31 $ 35 36
% Change (10.00%) (3.70%)  
United States | PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,311 $ 1,446 1,494
% Change (9.40%) (3.20%)  
United States | Other Infectious Diseases | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 11 $ 19 30
% Change (41.00%) (34.50%)  
United States | CONCERTA/Methylphenidate | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 134 $ 230 151
% Change (41.70%) 52.50%  
United States | INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,125 $ 2,897 2,714
% Change 7.90% 6.70%  
United States | SPRAVATO | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 929 $ 589 328
% Change 57.80% 79.70%  
United States | OTHER NEUROSCIENCE | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 210 $ 349 376
% Change (39.80%) (7.30%)  
United States | CARVYKTI | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 869 $ 469 133
% Change 85.20%    
United States | DARZALEX | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,588 $ 5,277 4,210
% Change 24.80% 25.40%  
United States | ERLEADA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,282 $ 1,065 968
% Change 20.30% 10.00%  
United States | IMBRUVICA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,020 $ 1,051 1,390
% Change (3.00%) (24.40%)  
United States | TECVAYLI | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 418 $ 334 12
% Change 25.30%    
United States | ZYTIGA/abiraterone acetate | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 34 $ 50 74
% Change (32.20%) (32.10%)  
United States | Other Oncology | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 643 $ 215 144
% Change   49.30%  
United States | OPSUMIT | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,520 $ 1,292 1,132
% Change 17.70% 14.10%  
United States | UPTRAVI | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,511 $ 1,326 1,104
% Change 13.90% 20.10%  
United States | Other Pulmonary Hypertension | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 112 $ 79 110
% Change 41.80% (28.60%)  
United States | XARELTO | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,373 $ 2,365 2,473
% Change 0.30% (4.40%)  
United States | Other | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 494 $ 541 569
% Change (8.80%) (5.00%)  
United States | ELECTROPHYSIOLOGY | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,738 $ 2,458 2,036
% Change 11.40% 20.70%  
United States | Abiomed | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,213 $ 1,066 31
% Change 13.70%    
United States | Shockwave Medical, Inc. | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 442 0 0
United States | other cardiovascular | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 120 $ 109 102
% Change 10.70% 6.70%  
United States | HIPS | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,057 $ 996 943
% Change 6.20% 5.60%  
United States | KNEES | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 922 $ 896 851
% Change 2.90% 5.30%  
United States | TRAUMA | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,013 $ 1,949 1,882
% Change 3.30% 3.60%  
United States | SPINE,SPORTS & OTHER | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,696 $ 1,684 1,645
% Change 0.70% 2.40%  
United States | ADVANCED | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,838 $ 1,833 1,784
% Change 0.20% 2.80%  
United States | GENERAL | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,165 $ 2,198 2,113
% Change (1.50%) 4.00%  
United States | CONTACT LENSES/OTHER | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,684 $ 1,626 1,522
% Change 3.60% 6.80%  
United States | SURGICAL | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 444 $ 460 468
% Change (3.40%) (1.80%)  
Non-US      
Segment Reporting Information [Line Items]      
Sales to Customers $ 38,519 $ 38,715 38,009
% Change (0.50%) 1.90%  
Non-US | Innovative Medicine      
Segment Reporting Information [Line Items]      
Sales to Customers $ 22,994 $ 23,590 23,959
% Change (2.50%) (1.50%)  
Non-US | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,473 $ 6,513 5,899
% Change (0.60%) 10.40%  
Non-US | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,042 $ 2,918 3,769
% Change (30.00%) (22.60%)  
Non-US | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,718 $ 3,076 3,323
% Change (11.60%) (7.50%)  
Non-US | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,926 $ 9,199 9,052
% Change 7.90% 1.60%  
Non-US | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,140 $ 1,117 1,071
% Change 2.00% 4.30%  
Non-US | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 696 $ 765 845
% Change (9.10%) (9.40%)  
Non-US | MedTech      
Segment Reporting Information [Line Items]      
Sales to Customers $ 15,525 $ 15,125 14,050
% Change 2.60% 7.70%  
Non-US | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,194 $ 2,717 2,131
% Change 17.60% 27.50%  
Non-US | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,470 $ 3,417 3,267
% Change 1.50% 4.60%  
Non-US | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,842 $ 6,006 5,793
% Change (2.70%) 3.70%  
Non-US | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,018 $ 2,986 2,859
% Change 1.10% 4.50%  
Non-US | Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 497 $ 549 722
% Change (9.50%) (23.90%)  
Non-US | Simponi/Simponi Aria | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,108 $ 1,073 1,017
% Change 3.30% 5.40%  
Non-US | Stelara | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,641 $ 3,892 3,335
% Change (6.40%) 16.70%  
Non-US | Tremfya | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,227 $ 999 824
% Change 22.80% 21.20%  
Non-US | Other Immunology | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 0 $ 0 0
% Change 0.00%    
Non-US | COVID-19 | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 198 $ 1,117 2,059
% Change (82.40%) (45.80%)  
Non-US | EDURANT/rilpivirine | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,241 $ 1,115 972
% Change 11.20% 14.80%  
Non-US | PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 401 $ 408 449
% Change (1.70%) (9.20%)  
Non-US | Other Infectious Diseases | Innovative Medicine | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 203 $ 278 289
% Change (26.70%) (3.80%)  
Non-US | CONCERTA/Methylphenidate | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 507 $ 554 493
% Change (8.40%) 12.20%  
Non-US | INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,097 $ 1,218 1,426
% Change (9.90%) (14.60%)  
Non-US | SPRAVATO | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 148 $ 100 46
% Change 48.20%    
Non-US | OTHER NEUROSCIENCE | Innovative Medicine | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 965 $ 1,204 1,358
% Change (19.80%) (11.30%)  
Non-US | CARVYKTI | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 94 $ 30 0
Non-US | DARZALEX | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,082 $ 4,467 3,767
% Change 13.80% 18.60%  
Non-US | ERLEADA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,717 $ 1,322 913
% Change 29.80% 44.80%  
Non-US | IMBRUVICA | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,018 $ 2,214 2,394
% Change (8.80%) (7.50%)  
Non-US | TECVAYLI | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 131 $ 61 3
Non-US | ZYTIGA/abiraterone acetate | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 597 $ 837 1,696
% Change (28.60%) (50.70%)  
Non-US | Other Oncology | Innovative Medicine | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 288 $ 269 280
% Change 7.10% (3.90%)  
Non-US | OPSUMIT | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 664 $ 681 651
% Change (2.40%) 4.60%  
Non-US | UPTRAVI | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 307 $ 255 218
% Change 20.10% 17.30%  
Non-US | Other Pulmonary Hypertension | Innovative Medicine | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 169 $ 182 202
% Change (6.90%) (10.30%)  
Non-US | XARELTO | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 0 $ 0 0
% Change 0.00% 0.00%  
Non-US | Other | Innovative Medicine | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 696 $ 765 845
% Change (9.10%) (9.40%)  
Non-US | ELECTROPHYSIOLOGY | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,529 $ 2,230 1,901
% Change 13.40% 17.30%  
Non-US | Abiomed | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 284 $ 240 0
% Change 18.20%    
Non-US | Shockwave Medical, Inc. | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 122 0 0
Non-US | other cardiovascular | MedTech | Cardiovascular      
Segment Reporting Information [Line Items]      
Sales to Customers $ 260 $ 247 230
% Change 5.30% 7.30%  
Non-US | HIPS | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 581 $ 564 571
% Change 3.00% (1.20%)  
Non-US | KNEES | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 623 $ 559 508
% Change 11.30% 10.20%  
Non-US | TRAUMA | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,036 $ 1,030 989
% Change 0.60% 4.10%  
Non-US | SPINE,SPORTS & OTHER | MedTech | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,230 $ 1,263 1,198
% Change (2.60%) 5.40%  
Non-US | ADVANCED | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,650 $ 2,837 2,785
% Change (6.60%) 1.90%  
Non-US | GENERAL | MedTech | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,192 $ 3,168 3,008
% Change 0.80% 5.30%  
Non-US | CONTACT LENSES/OTHER | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,049 $ 2,076 2,022
% Change (1.30%) 2.70%  
Non-US | SURGICAL | MedTech | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 969 $ 910 837
% Change 6.50% 8.60%  
UNITED STATES Exports | Remicade | Innovative Medicine | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 98 $ 147 $ 204
% Change (33.00%) (28.00%)