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Segments of Business and Geographic Areas - Sales by Segment of Business (Details) - USD ($)
$ in Millions
12 Months Ended
Jan. 02, 2022
Jan. 03, 2021
Dec. 29, 2019
Segment Reporting Information [Line Items]      
Sales to Customers $ 93,775 $ 82,584 $ 82,059
Percentage Change In Sales By Segment Of Business 13.60% 0.60%  
Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 14,635 $ 14,053 13,898
Percentage Change In Sales By Segment Of Business 4.10% 1.10%  
Pharmaceutical      
Segment Reporting Information [Line Items]      
Sales to Customers $ 52,080 $ 45,572 42,198
Percentage Change In Sales By Segment Of Business 14.30% 8.00%  
Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 16,750 $ 15,055 13,950
Percentage Change In Sales By Segment Of Business 11.30% 7.90%  
Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,861 $ 3,574 3,413
Percentage Change In Sales By Segment Of Business 64.00% 4.70%  
Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 7,011 $ 6,548 6,328
Percentage Change In Sales By Segment Of Business 7.10% 3.50%  
Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 14,548 $ 12,367 10,692
Percentage Change In Sales By Segment Of Business 17.60% 15.70%  
Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,450 $ 3,148 2,623
Percentage Change In Sales By Segment Of Business 9.60% 20.00%  
Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,460 $ 4,878 5,192
Percentage Change In Sales By Segment Of Business (8.60%) (6.00%)  
Medical Devices      
Segment Reporting Information [Line Items]      
Sales to Customers $ 27,060 $ 22,959 25,963
Percentage Change In Sales By Segment Of Business 17.90% (11.60%)  
Medical Devices | Interventional Solutions      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,971 $ 3,046 2,997
Percentage Change In Sales By Segment Of Business 30.40% 1.60%  
Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 8,588 $ 7,763 8,839
Percentage Change In Sales By Segment Of Business 10.60% (12.20%)  
Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,812 $ 8,232 9,501
Percentage Change In Sales By Segment Of Business 19.20% (13.40%)  
Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,688 $ 3,919 4,624
Percentage Change In Sales By Segment Of Business 19.60% (15.20%)  
OTC | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,227 $ 4,824 4,444
Percentage Change In Sales By Segment Of Business 8.40% 8.50%  
Skin health/Beauty | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,541 $ 4,450 4,593
Percentage Change In Sales By Segment Of Business 2.00% (3.10%)  
Oral Care | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,645 $ 1,641 1,528
Percentage Change In Sales By Segment Of Business 0.20% 7.40%  
Baby Care | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,566 $ 1,517 1,675
Percentage Change In Sales By Segment Of Business 3.20% (9.40%)  
Women's Health | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 917 $ 901 986
Percentage Change In Sales By Segment Of Business 1.80% (8.60%)  
Wound Care and Other | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 739 $ 720 671
Percentage Change In Sales By Segment Of Business 2.60% 7.20%  
Remicade | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,190 $ 3,747 4,380
Percentage Change In Sales By Segment Of Business (14.90%) (14.40%)  
Simponi/Simponi Aria | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,276 $ 2,243 2,188
Percentage Change In Sales By Segment Of Business 1.40% 2.60%  
Stelara | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 9,134 $ 7,707 6,361
Percentage Change In Sales By Segment Of Business 18.50% 21.10%  
Tremfya | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,127 $ 1,347 1,012
Percentage Change In Sales By Segment Of Business 57.90% 33.20%  
Other Immunology | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 24 $ 11 10
Percentage Change In Sales By Segment Of Business   6.40%  
COVID-19 | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers 2,385 $ 0 0
EDURANT/rilpivirine | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 994 $ 964 861
Percentage Change In Sales By Segment Of Business 3.10% 11.90%  
PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,083 $ 2,184 2,110
Percentage Change In Sales By Segment Of Business (4.60%) 3.50%  
Other Infectious Diseases | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 399 $ 427 441
Percentage Change In Sales By Segment Of Business (6.50%) (3.20%)  
CONCERTA/Methylphenidate | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 667 $ 622 696
Percentage Change In Sales By Segment Of Business 7.30% (10.60%)  
INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,022 $ 3,653 3,330
Percentage Change In Sales By Segment Of Business 10.10% 9.70%  
RISPERDAL CONSTA | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 592 $ 642 688
Percentage Change In Sales By Segment Of Business (7.70%) (6.80%)  
OTHER NEUROSCIENCE | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,729 $ 1,632 1,614
Percentage Change In Sales By Segment Of Business 6.00% 1.10%  
DARZALEX | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,023 $ 4,190 2,998
Percentage Change In Sales By Segment Of Business 43.80% 39.80%  
ERLEADA | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,291 $ 760 332
Percentage Change In Sales By Segment Of Business 70.00%    
IMBRUVICA | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,369 $ 4,128 3,411
Percentage Change In Sales By Segment Of Business 5.80% 21.00%  
ZYTIGA/abiraterone acetate | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,297 $ 2,470 2,795
Percentage Change In Sales By Segment Of Business (7.00%) (11.60%)  
Other Oncology | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 568 $ 821 1,158
Percentage Change In Sales By Segment Of Business (30.80%) (29.10%)  
OPSUMIT | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,819 $ 1,639 1,327
Percentage Change In Sales By Segment Of Business 11.00% 23.50%  
UPTRAVI | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,237 $ 1,093 819
Percentage Change In Sales By Segment Of Business 13.10% 33.50%  
Other | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 395 $ 416 476
Percentage Change In Sales By Segment Of Business (5.00%) (12.80%)  
Other | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 981 $ 1,186 1,353
Percentage Change In Sales By Segment Of Business (17.30%) (12.40%)  
XARELTO | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,438 $ 2,345 2,313
Percentage Change In Sales By Segment Of Business 4.00% 1.40%  
INVOKANA/INVOKAMET | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 563 $ 795 735
Percentage Change In Sales By Segment Of Business (29.30%) 8.20%  
PROCRIT/EPREX | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 479 $ 552 790
Percentage Change In Sales By Segment Of Business (13.30%) (30.20%)  
HIPS | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,485 $ 1,280 1,438
Percentage Change In Sales By Segment Of Business 16.00% (11.00%)  
KNEES | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,325 $ 1,170 1,480
Percentage Change In Sales By Segment Of Business 13.30% (21.00%)  
TRAUMA | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,885 $ 2,614 2,720
Percentage Change In Sales By Segment Of Business 10.40% (3.90%)  
SPINE,SPORTS & OTHER | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,893 $ 2,699 3,201
Percentage Change In Sales By Segment Of Business 7.20% (15.70%)  
ADVANCED | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 4,622 $ 3,839 4,095
Percentage Change In Sales By Segment Of Business 20.40% (6.20%)  
GENERAL | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,190 $ 4,392 5,406
Percentage Change In Sales By Segment Of Business 18.10% (18.80%)  
CONTACT LENSES/OTHER | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,440 $ 2,994 3,392
Percentage Change In Sales By Segment Of Business 14.90% (11.70%)  
SURGICAL | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,248 $ 925 1,232
Percentage Change In Sales By Segment Of Business 34.90% (24.90%)  
United States      
Segment Reporting Information [Line Items]      
Sales to Customers $ 47,156 $ 43,133 42,097
Percentage Change In Sales By Segment Of Business 9.30% 2.50%  
United States | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 6,516 $ 6,362 5,839
Percentage Change In Sales By Segment Of Business 2.40% 9.00%  
United States | Pharmaceutical      
Segment Reporting Information [Line Items]      
Sales to Customers $ 27,954 $ 25,735 23,874
Percentage Change In Sales By Segment Of Business 8.60% 7.80%  
United States | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 10,843 $ 10,175 9,641
Percentage Change In Sales By Segment Of Business 6.60% 5.50%  
United States | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,249 $ 1,735 1,597
Percentage Change In Sales By Segment Of Business 29.70% 8.60%  
United States | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,347 $ 3,091 2,919
Percentage Change In Sales By Segment Of Business 8.30% 5.90%  
United States | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,958 $ 5,092 4,299
Percentage Change In Sales By Segment Of Business 17.00% 18.50%  
United States | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,365 $ 2,133 1,684
Percentage Change In Sales By Segment Of Business 10.90% 26.60%  
United States | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,192 $ 3,509 3,734
Percentage Change In Sales By Segment Of Business (9.00%) (6.00%)  
United States | Medical Devices      
Segment Reporting Information [Line Items]      
Sales to Customers $ 12,686 $ 11,036 12,384
Percentage Change In Sales By Segment Of Business 14.90% (10.90%)  
United States | Medical Devices | Interventional Solutions      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,836 $ 1,452 1,443
Percentage Change In Sales By Segment Of Business 26.40% 0.60%  
United States | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,126 $ 4,779 5,319
Percentage Change In Sales By Segment Of Business 7.30% (10.20%)  
United States | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,867 $ 3,249 3,828
Percentage Change In Sales By Segment Of Business 19.00% (15.10%)  
United States | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,857 $ 1,557 1,794
Percentage Change In Sales By Segment Of Business 19.30% (13.20%)  
United States | OTC | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,594 $ 2,460 2,010
Percentage Change In Sales By Segment Of Business 5.40% 22.40%  
United States | Skin health/Beauty | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,400 $ 2,350 2,392
Percentage Change In Sales By Segment Of Business 2.10% (1.70%)  
United States | Oral Care | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 637 $ 683 621
Percentage Change In Sales By Segment Of Business (6.70%) 9.90%  
United States | Baby Care | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 378 $ 376 362
Percentage Change In Sales By Segment Of Business 0.50% 3.70%  
United States | Women's Health | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 13 $ 13 12
Percentage Change In Sales By Segment Of Business (1.60%) 8.20%  
United States | Wound Care and Other | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 495 $ 480 441
Percentage Change In Sales By Segment Of Business 3.10% 8.90%  
United States | Remicade | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,019 $ 2,508 3,079
Percentage Change In Sales By Segment Of Business (19.50%) (18.50%)  
United States | Simponi/Simponi Aria | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,127 $ 1,155 1,159
Percentage Change In Sales By Segment Of Business (2.40%) (0.30%)  
United States | Stelara | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,938 $ 5,240 4,346
Percentage Change In Sales By Segment Of Business 13.30% 20.60%  
United States | Tremfya | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,503 $ 926 764
Percentage Change In Sales By Segment Of Business 62.30% 21.30%  
United States | Other Immunology | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 21 $ 0 0
Percentage Change In Sales By Segment Of Business   0.00%  
United States | COVID-19 | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers 634 $ 0 0
United States | EDURANT/rilpivirine | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 41 $ 44 50
Percentage Change In Sales By Segment Of Business (7.60%) (11.20%)  
United States | PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,508 $ 1,587 1,422
Percentage Change In Sales By Segment Of Business (4.90%) 11.60%  
United States | Other Infectious Diseases | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 66 $ 104 126
Percentage Change In Sales By Segment Of Business (36.00%) (17.60%)  
United States | CONCERTA/Methylphenidate | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 172 $ 183 233
Percentage Change In Sales By Segment Of Business (5.80%) (21.40%)  
United States | INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,550 $ 2,314 2,107
Percentage Change In Sales By Segment Of Business 10.20% 9.80%  
United States | RISPERDAL CONSTA | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 287 $ 296 314
Percentage Change In Sales By Segment Of Business (2.90%) (5.90%)  
United States | OTHER NEUROSCIENCE | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 338 $ 298 266
Percentage Change In Sales By Segment Of Business 13.30% 12.40%  
United States | DARZALEX | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,169 $ 2,232 1,567
Percentage Change In Sales By Segment Of Business 42.00% 42.40%  
United States | ERLEADA | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 813 $ 583 297
Percentage Change In Sales By Segment Of Business 39.30% 96.10%  
United States | IMBRUVICA | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,747 $ 1,821 1,555
Percentage Change In Sales By Segment Of Business (4.00%) 17.10%  
United States | ZYTIGA/abiraterone acetate | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 119 $ 373 810
Percentage Change In Sales By Segment Of Business (68.10%) (54.00%)  
United States | Other Oncology | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 110 $ 83 70
Percentage Change In Sales By Segment Of Business 31.70% 18.60%  
United States | OPSUMIT | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,147 $ 1,008 766
Percentage Change In Sales By Segment Of Business 13.70% 31.70%  
United States | UPTRAVI | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,056 $ 955 714
Percentage Change In Sales By Segment Of Business 10.50% 33.80%  
United States | Other | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 163 $ 169 205
Percentage Change In Sales By Segment Of Business (3.70%) (17.60%)  
United States | Other | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 223 $ 323 380
Percentage Change In Sales By Segment Of Business (31.00%) (15.10%)  
United States | XARELTO | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,438 $ 2,345 2,313
Percentage Change In Sales By Segment Of Business 4.00% 1.40%  
United States | INVOKANA/INVOKAMET | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 308 $ 564 536
Percentage Change In Sales By Segment Of Business (45.40%) 5.20%  
United States | PROCRIT/EPREX | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 223 $ 277 505
Percentage Change In Sales By Segment Of Business (19.70%) (45.10%)  
United States | HIPS | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 883 $ 793 863
Percentage Change In Sales By Segment Of Business 11.40% (8.20%)  
United States | KNEES | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 787 $ 743 889
Percentage Change In Sales By Segment Of Business 5.90% (16.40%)  
United States | TRAUMA | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,819 $ 1,648 1,652
Percentage Change In Sales By Segment Of Business 10.40% (0.20%)  
United States | SPINE,SPORTS & OTHER | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,637 $ 1,595 1,915
Percentage Change In Sales By Segment Of Business 2.60% (16.70%)  
United States | ADVANCED | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,761 $ 1,535 1,637
Percentage Change In Sales By Segment Of Business 14.90% (6.20%)  
United States | GENERAL | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,105 $ 1,714 2,192
Percentage Change In Sales By Segment Of Business 22.70% (21.80%)  
United States | CONTACT LENSES/OTHER | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,398 $ 1,213 1,304
Percentage Change In Sales By Segment Of Business 15.20% (7.00%)  
United States | SURGICAL | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 459 $ 344 490
Percentage Change In Sales By Segment Of Business 33.50% (29.70%)  
Non-US      
Segment Reporting Information [Line Items]      
Sales to Customers $ 46,619 $ 39,451 39,962
Percentage Change In Sales By Segment Of Business 18.20% (1.30%)  
Non-US | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 8,119 $ 7,691 8,059
Percentage Change In Sales By Segment Of Business 5.60% (4.60%)  
Non-US | Pharmaceutical      
Segment Reporting Information [Line Items]      
Sales to Customers $ 24,126 $ 19,837 18,324
Percentage Change In Sales By Segment Of Business 21.60% 8.30%  
Non-US | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,907 $ 4,880 4,309
Percentage Change In Sales By Segment Of Business 21.00% 13.20%  
Non-US | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,612 $ 1,839 1,815
Percentage Change In Sales By Segment Of Business 96.30% 1.30%  
Non-US | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,664 $ 3,457 3,409
Percentage Change In Sales By Segment Of Business 6.00% 1.40%  
Non-US | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 8,590 $ 7,275 6,393
Percentage Change In Sales By Segment Of Business 18.10% 13.80%  
Non-US | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,085 $ 1,015 939
Percentage Change In Sales By Segment Of Business 6.90% 8.20%  
Non-US | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,268 $ 1,369 1,458
Percentage Change In Sales By Segment Of Business (7.40%) (6.10%)  
Non-US | Medical Devices      
Segment Reporting Information [Line Items]      
Sales to Customers $ 14,374 $ 11,923 13,579
Percentage Change In Sales By Segment Of Business 20.60% (12.20%)  
Non-US | Medical Devices | Interventional Solutions      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,135 $ 1,594 1,554
Percentage Change In Sales By Segment Of Business 34.00% 2.60%  
Non-US | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,462 $ 2,984 3,520
Percentage Change In Sales By Segment Of Business 16.00% (15.20%)  
Non-US | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 5,945 $ 4,983 5,673
Percentage Change In Sales By Segment Of Business 19.30% (12.20%)  
Non-US | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,831 $ 2,362 2,830
Percentage Change In Sales By Segment Of Business 19.80% (16.50%)  
Non-US | OTC | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,634 $ 2,364 2,434
Percentage Change In Sales By Segment Of Business 11.40% (2.90%)  
Non-US | Skin health/Beauty | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,141 $ 2,100 2,201
Percentage Change In Sales By Segment Of Business 1.90% (4.60%)  
Non-US | Oral Care | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,008 $ 958 906
Percentage Change In Sales By Segment Of Business 5.10% 5.70%  
Non-US | Baby Care | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,188 $ 1,141 1,313
Percentage Change In Sales By Segment Of Business 4.10% (13.10%)  
Non-US | Women's Health | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 905 $ 888 974
Percentage Change In Sales By Segment Of Business 1.80% (8.80%)  
Non-US | Wound Care and Other | Consumer Health      
Segment Reporting Information [Line Items]      
Sales to Customers $ 243 $ 240 230
Percentage Change In Sales By Segment Of Business 1.70% 4.10%  
Non-US | Remicade | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 935 $ 893 1,007
Percentage Change In Sales By Segment Of Business 4.80% (11.40%)  
Non-US | Simponi/Simponi Aria | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,148 $ 1,088 1,029
Percentage Change In Sales By Segment Of Business 5.50% 5.80%  
Non-US | Stelara | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,196 $ 2,467 2,015
Percentage Change In Sales By Segment Of Business 29.60% 22.40%  
Non-US | Tremfya | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 624 $ 421 248
Percentage Change In Sales By Segment Of Business 48.20% 69.90%  
Non-US | Other Immunology | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3 $ 11 10
Percentage Change In Sales By Segment Of Business (73.30%) 6.40%  
Non-US | COVID-19 | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,751 $ 0 0
Non-US | EDURANT/rilpivirine | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 953 $ 920 812
Percentage Change In Sales By Segment Of Business 3.60% 13.30%  
Non-US | PREZISTA/PREZCOBIX/REZOLSTA/SYMTUZA | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 575 $ 597 689
Percentage Change In Sales By Segment Of Business (3.60%) (13.40%)  
Non-US | Other Infectious Diseases | Pharmaceutical | Infectious Diseases      
Segment Reporting Information [Line Items]      
Sales to Customers $ 333 $ 323 315
Percentage Change In Sales By Segment Of Business 3.00% 2.60%  
Non-US | CONCERTA/Methylphenidate | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 495 $ 439 463
Percentage Change In Sales By Segment Of Business 12.80% (5.10%)  
Non-US | INVEGA SUSTENNA/XEPLION/TRINZA/TREVICTA | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,472 $ 1,339 1,224
Percentage Change In Sales By Segment Of Business 10.00% 9.40%  
Non-US | RISPERDAL CONSTA | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 305 $ 346 374
Percentage Change In Sales By Segment Of Business (11.80%) (7.50%)  
Non-US | OTHER NEUROSCIENCE | Pharmaceutical | Neuroscience      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,391 $ 1,334 1,349
Percentage Change In Sales By Segment Of Business 4.30% (1.10%)  
Non-US | DARZALEX | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,854 $ 1,958 1,430
Percentage Change In Sales By Segment Of Business 45.80% 36.90%  
Non-US | ERLEADA | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 478 $ 176 35
Non-US | IMBRUVICA | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,622 $ 2,307 1,856
Percentage Change In Sales By Segment Of Business 13.60% 24.30%  
Non-US | ZYTIGA/abiraterone acetate | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,178 $ 2,097 1,985
Percentage Change In Sales By Segment Of Business 3.90% 5.60%  
Non-US | Other Oncology | Pharmaceutical | Oncology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 458 $ 738 1,087
Percentage Change In Sales By Segment Of Business (37.90%) (32.10%)  
Non-US | OPSUMIT | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 672 $ 631 562
Percentage Change In Sales By Segment Of Business 6.60% 12.30%  
Non-US | UPTRAVI | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 181 $ 138 105
Percentage Change In Sales By Segment Of Business 31.10% 30.90%  
Non-US | Other | Pharmaceutical | Pulmonary Hypertension      
Segment Reporting Information [Line Items]      
Sales to Customers $ 232 $ 247 272
Percentage Change In Sales By Segment Of Business (5.90%) (9.20%)  
Non-US | Other | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 758 $ 864 974
Percentage Change In Sales By Segment Of Business (12.20%) (11.30%)  
Non-US | XARELTO | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 0 $ 0 0
Percentage Change In Sales By Segment Of Business 0.00% 0.00%  
Non-US | INVOKANA/INVOKAMET | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 254 $ 231 199
Percentage Change In Sales By Segment Of Business 9.90% 16.30%  
Non-US | PROCRIT/EPREX | Pharmaceutical | Cardiovascular/Metabolism/Other      
Segment Reporting Information [Line Items]      
Sales to Customers $ 256 $ 274 285
Percentage Change In Sales By Segment Of Business (6.80%) (3.80%)  
Non-US | HIPS | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 602 $ 487 575
Percentage Change In Sales By Segment Of Business 23.60% (15.30%)  
Non-US | KNEES | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 538 $ 427 591
Percentage Change In Sales By Segment Of Business 26.10% (27.80%)  
Non-US | TRAUMA | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,066 $ 966 1,068
Percentage Change In Sales By Segment Of Business 10.40% (9.60%)  
Non-US | SPINE,SPORTS & OTHER | Medical Devices | Orthopaedics      
Segment Reporting Information [Line Items]      
Sales to Customers $ 1,256 $ 1,104 1,286
Percentage Change In Sales By Segment Of Business 13.80% (14.10%)  
Non-US | ADVANCED | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,861 $ 2,304 2,458
Percentage Change In Sales By Segment Of Business 24.10% (6.20%)  
Non-US | GENERAL | Medical Devices | Surgery      
Segment Reporting Information [Line Items]      
Sales to Customers $ 3,085 $ 2,679 3,215
Percentage Change In Sales By Segment Of Business 15.20% (16.70%)  
Non-US | CONTACT LENSES/OTHER | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 2,043 $ 1,781 2,088
Percentage Change In Sales By Segment Of Business 14.70% (14.70%)  
Non-US | SURGICAL | Medical Devices | Vision      
Segment Reporting Information [Line Items]      
Sales to Customers $ 788 $ 581 742
Percentage Change In Sales By Segment Of Business 35.70% (21.70%)  
UNITED STATES Exports | Remicade | Pharmaceutical | Immunology      
Segment Reporting Information [Line Items]      
Sales to Customers $ 236 $ 346 $ 294
Percentage Change In Sales By Segment Of Business (31.90%) 18.00%