Cuprina Holdings (Cayman) Limited

c/o Blk 1090 Lower Delta Road #06-08

Singapore 169201

March 28, 2025

U.S. Securities & Exchange Commission

Office of Life Sciences

Division of Corporation Finance

100 F Street, NE

Attn: Doris Stacey Gama and Alan Campbell

Re:	Cuprina Holdings (Cayman) Limited
	Registration Statement on Form F-1
	Initially Filed December 6, 2024, as amended
	File No. 333-283643

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Cuprina Holdings (Cayman) Limited. hereby requests acceleration of effectiveness of the above referenced Registration Statement so that it will become effective at 4:30 p.m., Eastern Time, on March 31, 2025, or as soon as thereafter practicable.

Very truly yours,

/s/ David Quek Yong Qi

David Quek Yong Qi

Director and Chief Executive Officer

cc:	Loeb & Loeb LLP
	Winston & Strawn LLP