144 0001238403 XXXXXXXX LIVE 0001994702 KYVERNA THERAPEUTICS, INC. 001-41947 5980 Horton St., STE 550 Emeryville, CA 94608 (510) 925-2492 DANIEL SPIEGELMAN Director Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

17578 162636.93 60439893 04/07/2026 NASDAQ Common 04/07/2026 Stock Option Exercise Issuer N 17578 04/07/2026 Cash N DANIEL SPIEGELMAN

5980 Horton St., STE 550 Emeryville, CA 94608

Common 03/31/2026 16634 140404.27 04/07/2026 /s/ Dan Spiegelman