Segment Reporting (Tables)

6 Months Ended

Jun. 30, 2025

Segment Reporting [Abstract]

Summary of Segment Loss Including Significant Segment Expenses

The following table sets forth the Company’s summary of segment loss, including significant segment expenses for the three and six months ended June 30, 2025 and 2024 (in thousands):

		Three Months Ended June 30,								Six Months Ended June 30,
		2025				2024				2025				2024
Research and development expenses:
KYV-101 program	$		22,541		$		13,326		$		44,661		$		24,323
Other programs			986				512				1,498				3,140
Other research and development expenses(a)			12,289				13,483				27,090				22,334
General and administrative expenses(b)			8,594				6,114				18,569				12,996
Interest (income)			(2,364	)			(4,694	)			(5,189	)			(7,429	)
Interest expense and other expenses, net			35				62				87				132
Segment Loss and Net loss	$		42,081		$		28,803		$		86,716		$		55,496

(a) Primarily includes personnel costs, R&D professional services, unallocated CRO and CMO costs and allocated overhead and facilities expenses

(b) Primarily includes personnel costs, allocated overhead and facilities expenses, legal, IT, accounting and general and administrative expenses