<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002089121</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001993431</issuerCik>
      <issuerName>Micropolis Holding Co</issuerName>
      <secFileNumber>001-42550</secFileNumber>
      <issuerAddress>
        <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
        <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
        <com:city>DUBAI</com:city>
        <com:stateOrCountry>C0</com:stateOrCountry>
        <com:zipCode>00000</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>97142767008</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Lo Gatto Simon Jonathan Rubel</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>10% Stockholder</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Charles Schwab &amp; Co</name>
        <address>
          <com:street1>3000 Schwab Way</com:street1>
          <com:city>Westlake</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>76262</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>100000</noOfUnitsSold>
      <aggregateMarketValue>224870.00</aggregateMarketValue>
      <noOfUnitsOutstanding>30000000</noOfUnitsOutstanding>
      <approxSaleDate>10/14/2025</approxSaleDate>
      <securitiesExchangeName>NYSE American</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <acquiredDate>09/05/2020</acquiredDate>
      <natureOfAcquisitionTransaction>Private Placement</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>100000</amountOfSecuritiesAcquired>
      <paymentDate>09/05/2020</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/01/2025</saleDate>
      <amountOfSecuritiesSold>3000</amountOfSecuritiesSold>
      <grossProceeds>4260.30</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/02/2025</saleDate>
      <amountOfSecuritiesSold>7395</amountOfSecuritiesSold>
      <grossProceeds>10573.31</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/03/2025</saleDate>
      <amountOfSecuritiesSold>10605</amountOfSecuritiesSold>
      <grossProceeds>16595.40</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/06/2025</saleDate>
      <amountOfSecuritiesSold>10000</amountOfSecuritiesSold>
      <grossProceeds>15685.60</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/07/2025</saleDate>
      <amountOfSecuritiesSold>5000</amountOfSecuritiesSold>
      <grossProceeds>7501.50</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/08/2025</saleDate>
      <amountOfSecuritiesSold>3573</amountOfSecuritiesSold>
      <grossProceeds>5180.85</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/09/2025</saleDate>
      <amountOfSecuritiesSold>31677</amountOfSecuritiesSold>
      <grossProceeds>56353.11</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Simon Jonathan Rubel Lo Gatto</name>
        <address>
          <com:street1>1 DAR ALKHALEEJ, WAREHOUSE 1,</com:street1>
          <com:street2>DUBAI PRODUCTION CITY, P.O BOX 500372</com:street2>
          <com:city>DUBAI</com:city>
          <com:stateOrCountry>C0</com:stateOrCountry>
          <com:zipCode>00000</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <saleDate>10/13/2025</saleDate>
      <amountOfSecuritiesSold>4891</amountOfSecuritiesSold>
      <grossProceeds>8814.32</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>Shares to be sold were acquired between 09-5-2020 through 10-4-2021 </remarks>
    <noticeSignature>
      <noticeDate>10/14/2025</noticeDate>
      <signature>Simon Jonathan Rubel Lo Gatto</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
