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License and Collaboration Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Mar. 31, 2025
Mar. 31, 2024
License and Collaboration Agreements [Line Items]        
License and collaboration revenue     $ 52,000 $ 529,000
Lepu Biotech Co., Ltd.        
License and Collaboration Agreements [Line Items]        
One-time upfront payment   $ 4,500,000    
Collaboration agreement transaction price   4,500,000    
License and collaboration revenue     0 500,000
Lepu Biotech Co., Ltd. | Maximum        
License and Collaboration Agreements [Line Items]        
Regulatory milestone payments   2,500,000    
Commercial milestone payments   $ 57,500,000    
Kissei Pharmaceutical Co., Ltd.        
License and Collaboration Agreements [Line Items]        
One-time upfront payment $ 10,000,000      
License and collaboration revenue       $ (0)
Royalties 0      
Kissei Pharmaceutical Co., Ltd. | Maximum        
License and Collaboration Agreements [Line Items]        
Commercial milestone payments 67,000,000      
Development and regulatory milestone payments 33,000,000      
License and collaboration revenue     $ 100,000  
Kissei Pharmaceutical Co., Ltd. | Series D Redeemable Convertible Preferred Stock        
License and Collaboration Agreements [Line Items]        
Purchase of redeemable convertible preferred stock $ 30,000,000