<?xml version="1.0" encoding="UTF-8"?><!-- Produced by edgar-services.com, Advanced Computer Innovations, Inc., Copyright (C) 2024-2026 --><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
	<schemaVersion>X0202</schemaVersion>
<headerData>
		<submissionType>SCHEDULE 13G/A</submissionType>
		<previousAccessionNumber>1376474-26-000189</previousAccessionNumber>
		<filerInfo>
			<filer>
				<filerCredentials>
					<cik>0002111558</cik>
					<ccc>XXXXXXXX</ccc>
				</filerCredentials>
			</filer>
			<liveTestFlag>LIVE</liveTestFlag>


		</filerInfo>
	</headerData>
	<formData>
		<coverPageHeader>
			<amendmentNo>1</amendmentNo>
			<securitiesClassTitle>Common Shares</securitiesClassTitle>
			<eventDateRequiresFilingThisStatement>02/25/2026</eventDateRequiresFilingThisStatement>
			<issuerInfo>
				<issuerCik>0001985062</issuerCik>
				<issuerName>PSYENCE BIOMEDICAL LTD.</issuerName>
				<issuerCusips>
					<issuerCusipNumber>74449F308</issuerCusipNumber>
				</issuerCusips>
				<issuerPrincipalExecutiveOfficeAddress>
					<com:street1>121 RICHMOND STREET WEST PENTHOUSE</com:street1>
					<com:street2>SUITE 1300</com:street2>
					<com:city>TORONTO</com:city>
					<com:stateOrCountry>A6</com:stateOrCountry>
					<com:zipCode>CANADA</com:zipCode>
				</issuerPrincipalExecutiveOfficeAddress>
			</issuerInfo>
			<designateRulesPursuantThisScheduleFiled>
				<designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
			</designateRulesPursuantThisScheduleFiled>
		</coverPageHeader>
		<coverPageHeaderReportingPersonDetails>

			<reportingPersonName>Weiner Jeffrey David</reportingPersonName>
			<citizenshipOrOrganization>X1</citizenshipOrOrganization>
			<reportingPersonBeneficiallyOwnedNumberOfShares>
				<soleVotingPower>59750</soleVotingPower>
				<sharedVotingPower>0</sharedVotingPower>
				<soleDispositivePower>59750</soleDispositivePower>
				<sharedDispositivePower>0</sharedDispositivePower>
			</reportingPersonBeneficiallyOwnedNumberOfShares>
			<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>59750</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
			<classPercent>2.61</classPercent>
			<typeOfReportingPerson>IN</typeOfReportingPerson>
		</coverPageHeaderReportingPersonDetails>
		<items>
			<item1>
				<issuerName>PSYENCE BIOMEDICAL LTD.</issuerName>
				<issuerPrincipalExecutiveOfficeAddress>121 RICHMOND STREET WEST PENTHOUSE, SUITE 1300, TORONTO, ONTARIO, CANADA</issuerPrincipalExecutiveOfficeAddress>
			</item1>
			<item2>
				<filingPersonName>Weiner Jeffrey David</filingPersonName>
				<principalBusinessOfficeOrResidenceAddress>1856 E Hamlin Street, Seattle, WA 98112</principalBusinessOfficeOrResidenceAddress>
				<citizenship>United States</citizenship>
			</item2>
			<item3>
				<notApplicableFlag>Y</notApplicableFlag>
				<otherTypeOfPersonFiling>    </otherTypeOfPersonFiling>
			</item3>
			<item4>
				<amountBeneficiallyOwned>59,750</amountBeneficiallyOwned>
				<classPercent>2.61 - This percentage is based on 2,293,307 total outstanding shares reported by the company.</classPercent>
				<numberOfSharesPersonHas>
					<solePowerOrDirectToVote>59,750</solePowerOrDirectToVote>
					<sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
					<solePowerOrDirectToDispose>59,750</solePowerOrDirectToDispose>
					<sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
				</numberOfSharesPersonHas>
			</item4>
			<item5>
				<classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
			</item5>
			<item6>
				<notApplicableFlag>Y</notApplicableFlag>
			</item6>
			<item7>
				<notApplicableFlag>Y</notApplicableFlag>
			</item7>
			<item8>
				<notApplicableFlag>Y</notApplicableFlag>
			</item8>
			<item9>
				<notApplicableFlag>Y</notApplicableFlag>
			</item9>
			<item10>
				<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.</certifications>
			</item10>
		</items>
		<signatureInformation>
			<reportingPersonName>Weiner Jeffrey David</reportingPersonName>
			<signatureDetails>
				<signature>Weiner Jeffrey David</signature>
				<title>Individual</title>
				<date>06/09/2026</date>
			</signatureDetails>
		</signatureInformation>
	</formData>
</edgarSubmission>
