X0508 4 2024-07-01 0001830214 Ginkgo Bioworks Holdings, Inc. DNA 0001977441 Coen Steven P. C/O GINKGO BIOWORKS HOLDINGS, INC. 27 DRYDOCK AVENUE BOSTON MA 02210 1 See remarks 0 Class A Common Stock 2024-07-01 4 M 0 23496 A 202328 D Class A Common Stock 2024-07-01 4 M 0 6250 A 208578 D Class A Common Stock 2024-07-02 4 S 0 13520 .326 D 195058 D Restricted Stock Units 2024-07-01 4 M 0 23496 D Class A Common Stock 23496 798873 D Restricted Stock Units 2024-07-01 4 M 0 6250 D Class A Common Stock 6250 275001 D Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's Class A Common Stock. Represents shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock and/or restricted stock units. Sales to cover tax withholding obligations in connection with the vesting of such securities do not represent discretionary trades by the Reporting Person. The Issuer's equity incentive plans allow the Issuer to require that satisfaction of tax withholding obligations be funded by a "sell to cover" transaction. The RSUs vest as follows: 25% of the underlying shares vested on May 1, 2024, then 36 equal monthly installments thereafter. The RSUs vest as follows: 2/48ths of the underlying shares vested on May 1, 2024, then 46 equal monthly installments thereafter. Chief Accounting Officer /s/ Karen Tepichin, Attorney-in-Fact 2024-07-05