Related Parties - Additional Information (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Related Parties
Research and development	[1]	$ 214,712	$ 167,865	$ 68,424
Paragon Therapeutics, Inc | Minimum
Related Parties
Percentage of capital stock beneficially owns		5.00%
Related party
Related Parties
Research and development		$ 2,100
Related party | Paragon Therapeutics, Inc
Related Parties
Due to related party		2,100	100
Research and development		$ 2,200	$ 19,200	$ 26,300

[1] Includes related party amounts of $2,186 for the year ended December 31, 2025, $19,179 for the year ended December 31, 2024 and $26,285 for the year ended December 31, 2023.