144 0001802528 XXXXXXXX LIVE 0001974640 Apogee Therapeutics, Inc. 001-41740 221 Crescent Street Building 17, Suite 102b Waltham MA 02453 650-394-5230 Fairmount Healthcare Fund II L.P. Director Common Jefferies LLC

520 Madison Ave New York NY 10022

1750000 133525000.00 54833587 01/22/2026 NASDAQ Common 07/13/2023 Purchased in initial public offering Issuer N 1750000 07/18/2023 Cash Y Fairmount Funds Management LLC ("Fairmount") is the investment manager for Fairmount Healthcare Fund II L.P. The managers of Fairmount are Peter Harwin and Tomas Kiselak, who are also directors of the Issuer. 01/22/2026 /s/ Tomas Kiselak for Fairmount Funds Management LLC