Related Parties - Additional Information (Details) - USD ($) $ in Thousands		3 Months Ended
		Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024
Related Parties
Research and development	[1]	$ 46,387	$ 28,716
Related party | Paragon Therapeutics, Inc
Related Parties
Due to related party				$ 100
Research and development			$ 6,500

[1] Includes related-party amounts of $32 for the three months ended March 31, 2025, and $6,457 for the three months ended March 31, 2024.