Other Significant Agreements - WuXi Biologics (Hong Kong) limited agreements (Details) - USD ($)		1 Months Ended	3 Months Ended
		Jun. 30, 2022	Mar. 31, 2025	Mar. 31, 2024
Other Significant Agreements Paragon Option Agreement
Research and development	[1]		$ 46,387,000	$ 28,716,000
Biologics Master Services Agreement | WuXi Biologics
Other Significant Agreements Paragon Option Agreement
Prior notice period for termination of work order		6 months
Threshold number of days for no termination or cancellation fee upon uncured breach after notice of such breach		30 days
Threshold number of days for no termination or cancellation fee upon performance breach		90 days
Research and development			$ 1,200,000	$ 4,400,000
Cell Line License Agreement | WuXi Biologics
Other Significant Agreements Paragon Option Agreement
Prior notice period for termination of work order		6 months
Non-refundable license fee		$ 150,000
Threshold number of days for no termination or cancellation fee upon uncured breach after notice of such breach		60 days
Threshold number of days for termination upon uncured material breach after notice of such breach		30 days

[1] Includes related-party amounts of $32 for the three months ended March 31, 2025, and $6,457 for the three months ended March 31, 2024.