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Other Significant Agreements - Paragon Agreement (Details)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 12, 2024
USD ($)
Nov. 30, 2023
USD ($)
Nov. 30, 2022
USD ($)
Item
shares
Jun. 30, 2024
USD ($)
shares
Mar. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
shares
Sep. 30, 2023
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2024
USD ($)
shares
Jun. 30, 2023
USD ($)
Other Significant Agreements Paragon Option Agreement                    
Research and development [1]       $ 33,206       $ 13,946 $ 61,922 $ 22,401
Issued total common units (in shares) | shares       58,481,214   50,655,671     58,481,214  
Option Agreement                    
Other Significant Agreements Paragon Option Agreement                    
Aggregate acquisition cost     $ 3,500              
Paragon Therapeutics, Inc | Related party                    
Other Significant Agreements Paragon Option Agreement                    
Research and development       $ 2,200       $ 5,900 $ 8,700 $ 13,400
Paragon Therapeutics, Inc | Option Agreement                    
Other Significant Agreements Paragon Option Agreement                    
Payments due upon exercise of option     $ 0              
Termination period of agreement   30 days 30 days              
Period of material breach   30 days 30 days              
Threshold number of days for termination upon failure to make payment and such failure persists even after the notice   30 days 30 days              
Payment of non-refundable fees         $ 2,000          
Paragon Therapeutics, Inc | Option Agreement | Related party                    
Other Significant Agreements Paragon Option Agreement                    
Number of selected targets initially included under the agreement | Item     2              
Upfront cash amount paid     $ 1,300              
Issued common units (in shares) | shares     1,250,000              
Issued total common units (in shares) | shares     5,000,000              
Aggregate fair value on grant date     $ 2,200              
Non-refundable fee   $ 2,000 $ 500              
Paragon Therapeutics, Inc | Option Agreement | Maximum | Related party                    
Other Significant Agreements Paragon Option Agreement                    
Issued total common units (in shares) | shares     3,750,000              
Paragon Therapeutics, Inc | Paragon IL13 License Agreement                    
Other Significant Agreements Paragon Option Agreement                    
Expiration period of commercial sale     12 years              
Termination period of agreement     60 days              
Period of material breach     90 days              
Threshold number of days for termination upon failure to make payment and such failure persists even after the notice     30 days              
Paragon Therapeutics, Inc | Paragon IL13 License Agreement | Related party                    
Other Significant Agreements Paragon Option Agreement                    
Maximum amount of achievement of development and clinical mile stones     $ 3,000              
Nomination fee paid     1,000 $ 1,000 $ 2,000 $ 1,000 $ 2,000      
Milestone payment of trial payable     $ 2,000              
Paragon Therapeutics, Inc | TSLP License Agreement | Subsequent Event                    
Other Significant Agreements Paragon Option Agreement                    
Expiration period of commercial sale 12 years                  
Termination period of agreement 60 days                  
Period of material breach 90 days                  
Threshold number of days for termination upon failure to make payment and such failure persists even after the notice 30 days                  
Paragon Therapeutics, Inc | TSLP License Agreement | Related party | Subsequent Event                    
Other Significant Agreements Paragon Option Agreement                    
Maximum amount of achievement of development and clinical mile stones $ 28,000                  
Nomination fee paid 3,000                  
Milestone payment of trial payable $ 5,000                  
[1] Includes related-party amounts of $2,221 and $8,678 for the three and six months ended June 30, 2024, respectively, and $5,884 and $13,411 for the three and six months ended June 30, 2023, respectively.