SCHEDULE 13G/A 0001104659-23-120362 0001699737 XXXXXXXX LIVE 2 Common Stock, par value $0.001 09/30/2025 0001966494 CARGO THERAPEUTICS, INC. 14179K101 835 INDUSTRIAL ROAD, SUITE 400 SAN CARLOS CA 94070 Rule 13d-1(c) Samsara BioCapital, L.P. b DE 0.00 0.00 0.00 0.00 0.00 0.0 PN Samsara BioCapital GP, LLC b DE 0.00 0.00 0.00 0.00 0.00 0.0 OO Srinivas Akkaraju b X1 0.00 0.00 0.00 0.00 0.00 0.0 IN CARGO THERAPEUTICS, INC. 835 INDUSTRIAL ROAD, SUITE 400, SAN CARLOS, CA, 94070. The names of the persons filing this report (collectively, the "Reporting Persons") are: Samsara BioCapital, L.P. ("Samsara LP") Samsara BioCapital GP, LLC ("Samsara GP") Srinivas Akkaraju ("Dr. Akkaraju") The Reporting Persons expressly disclaim status as a "group" for purposes of this Schedule 13G. c/o Samsara BioCapital, LLC 628 Middlefield Road Palo Alto, CA 94301 Samsara LP Delaware Samsara GP Delaware Dr. Akkaraju United States Y Row 9 of each Reporting Person's cover page to this Schedule 13G sets forth the aggregate number of securities of the Issuer beneficially owned by such Reporting Person as of September 30, 2025 and is incorporated by reference. Row 11 of each Reporting Person's cover page to this Schedule 13G sets forth the percentages of securities of the Issuer beneficially owned by such Reporting Person as of September 30, 2025 and is incorporated by reference. Row 5 of each Reporting Person's cover page to this Schedule 13G sets forth the sole power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of September 30, 2025 and is incorporated by reference. Row 6 of each Reporting Person's cover page to this Schedule 13G sets forth the shared power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of September 30, 2025 and is incorporated by reference. Row 7 of each Reporting Person's cover page to this Schedule 13G sets forth the shared power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of September 30, 2025 and is incorporated by reference. Row 8 of each Reporting Person's cover page to this Schedule 13G sets forth the shared power to vote or to direct the vote of securities of the Issuer beneficially owned by such Reporting Person as of September 30, 2025 and is incorporated by reference. N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Exhibit 99.1 Joint Filing Statement, dated as of November 14, 2024 (incorporated by reference to Exhibit A to the Reporting Persons' Schedule 13G filed with the SEC on November 14, 2024). Samsara BioCapital, L.P. /s/ Srinivas Akkaraju 11/14/2025 Samsara BioCapital GP, LLC /s/ Srinivas Akkaraju 11/14/2025 Srinivas Akkaraju /s/ Srinivas Akkaraju 11/14/2025