License and Research and Development Agreements - Additional Information (Details) - USD ($)	1 Months Ended						3 Months Ended		12 Months Ended
	Mar. 31, 2024	Nov. 30, 2023	Feb. 28, 2023	Aug. 31, 2022	Jun. 30, 2022	Mar. 31, 2022	Mar. 31, 2024	Mar. 31, 2023	Dec. 31, 2023	Dec. 31, 2022
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expense							$ 30,503,000	$ 12,562,000
Other non-current liabilities									$ 225,000
Stanford License
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Upfront payment				$ 50,000
Issuance of common shares for license, shares				67,605
Issuance of common shares for license, fair value				$ 100,000
Research and development expense				200,000			0	0
Stanford License | Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Annual license maintenance fees				100,000
Stanford License | Maximum | Development Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments				4,000,000
Stanford License | Maximum | Sales Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments				$ 7,500,000
Oxford License and Supply Agreement
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expense							0	0
Upfront license fee					$ 200,000
Oxford License and Supply Agreement | Research and Development
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Upfront license fee					$ 200,000
Amendment to Oxford Agreement | Regulatory and Commercial Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments	$ 4,800,000
2022 NCI License
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Payment of extension royalty						$ 50,000
Non-refundable license fee						600,000	200,000		100,000	$ 200,000
Remaining balance of non refundable license fee							$ 100,000
Accrued non refundable license fee						400,000
Minimum payment on sale, transfer or lease of PRV						5,000,000
Termination and expiration clause							NCI may terminate or modify the 2022 NCI License in the event of an uncured material breach, including, but not limited to, if the Company does not meet certain milestones by certain dates, or upon certain insolvency events that remain uncured following the date that is 90 days following written notice of such breach or insolvency event. The Company may terminate the license, or any portion thereof, at its sole discretion at any time upon 60 days written notice to the NCI.
2022 NCI License | Accrued Expenses and Other Current Liabilities Member
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Accrued non-refundable upfront fees	100,000						$ 100,000
2022 NCI License | Other Noncurrent Liabilities
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Accrued non-refundable upfront fees	300,000						300,000		$ 200,000
2022 NCI License | Research and Development
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Non-refundable license fee						600,000
2022 NCI License | Minimum Annual Royalty
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expense							$ 100,000	100,000
2022 NCI License | Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments						200,000
2022 NCI License | Maximum | Development Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments						1,800,000
2022 NCI License | Maximum | Sales Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments						16,000,000
2022 NCI License | Minimum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Minimum annual royalty payments						50,000
Minimum payment on submission of PRV						$ 500,000
2023 NCI License
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Non-refundable license fee			$ 300,000
Minimum payment on sale, transfer or lease of PRV			5,000,000
Termination and expiration clause							Unless earlier terminated, the 2023 NCI License will expire upon the expiration of the last to expire licensed patent right. The NCI may terminate or modify the 2023 NCI License in the event of an uncured material breach, including, but not limited to, if the Company does not meet certain milestones by certain dates, or upon certain insolvency events that remain uncured following the date that is 90 days following written notice of such breach or insolvency event. The Company may terminate the license, or any portion thereof, at its sole discretion at any time upon 60 days written notice to the NCI.
Payment of reimburse in expense incurred on patent			100,000
2023 NCI License | Accrued Expenses and Other Current Liabilities Member
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expense		$ 300,000
2023 NCI License | Research and Development
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Non-refundable license fee			400,000
2023 NCI License | Minimum Annual Royalty
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expense							$ 50,000	$ 400,000
2023 NCI License | Maximum | Development Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments			1,700,000
2023 NCI License | Maximum | Regulatory Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments			100,000
2023 NCI License | Maximum | Sales Milestones
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments			16,000,000
2023 NCI License | Minimum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Minimum annual royalty payments			50,000
Minimum payment on submission of PRV			$ 500,000
Stanford University | Stanford License
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Issuance of common shares for license, shares				22,317
Non-profit Organizations | Stanford License
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Issuance of common shares for license, shares				27,100
Stanford University Inventors | Stanford License
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Issuance of common shares for license, shares				18,188
Commercial Milestone Event | Stanford License | Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments				$ 50,000
Certain Additional Milestone Events | Stanford License | Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Milestone payments				$ 500,000
CRG-023 Program | Amendment to Oxford Agreement | Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Additional target fees to be paid	$ 9,500,000						$ 9,500,000