XML 42 R31.htm IDEA: XBRL DOCUMENT v3.25.2
COMMITMENTS AND CONTINGENCIES (Details Narrative) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Product Liability Contingency [Line Items]        
Net sales
License agreement description     (1) obtain an IND for a patent product within 1 year of the effective date of the agreement, (2) commence a Phase II trial within 2 years of the effective date of the agreement, and (3) submit an NDA or BLA to the FDA or equivalent regulatory agency in another jurisdiction within 7 years of the effective date of the agreement. Pursuant to the Enviro-Cedars License Agreement (Mitochondrial DNA), Enviro is obligated to (1) complete preclinical studies of a patent product within 2 years of the effective date of the agreement, (2) complete toxicology studies within 2.5 years of the effective date of the agreement, (3) obtain IND within 3 years of the effective date of the agreement, (4) begin a Phase I trial within 4 years of the effective date of the agreement, and (5) submit an NDA or BLA to the FDA or equivalent regulatory agency in another jurisdiction within 7 years of the effective date of the agreement. If the Commercialization Milestones are not met or extended, Cedars may convert the exclusive licenses into non-exclusive licenses or to a co-exclusive licenses or terminate the licenses.  
Non-US [Member] | Food and Drug Administration [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     $ 1,500  
Phase I Clinical Trial [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     150  
Item 1 And 2 [Member] | Phase II [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     250  
Item 3 [Member] | Phase II Clinical Trial [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     500  
Item 1, 2 and 3 [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     250  
Net sales     5,000  
Item 4 [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     2,500  
Net sales     50,000  
Item 4 [Member] | Food and Drug Administration [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     1,500  
Item 4 [Member] | Phase II Clinical Trial [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     250  
Item 4 [Member] | Phase I Clinical Trial [Member]        
Product Liability Contingency [Line Items]        
Payment for milestone     150  
Exclusive License Agreement [Member]        
Product Liability Contingency [Line Items]        
License fee     5  
Annual maintenance fee     $ 10  
Royalty percentage     3.75%  
Exclusive License Agreement [Member] | Item 4 [Member]        
Product Liability Contingency [Line Items]        
License fee     $ 50  
Annual maintenance fee     $ 10  
Royalty percentage     4.25%  
Minimum requirerment of capital $ 500   $ 500  
Patent product sales     0.50%  
Exclusive License Agreement [Member] | Minimum [Member]        
Product Liability Contingency [Line Items]        
Patent protection costs     $ 9  
Other non-royalty sublicense fees percentage     5.00%  
Exclusive License Agreement [Member] | Minimum [Member] | Item 4 [Member]        
Product Liability Contingency [Line Items]        
Other non-royalty sublicense fees percentage     5.00%  
Exclusive License Agreement [Member] | Maximum [Member]        
Product Liability Contingency [Line Items]        
Patent protection costs     $ 61  
Other non-royalty sublicense fees percentage     35.00%  
Exclusive License Agreement [Member] | Maximum [Member] | Item 4 [Member]        
Product Liability Contingency [Line Items]        
Other non-royalty sublicense fees percentage     35.00%  
Enviro Cedars License Agreements [Member] | Item 1 And 2 [Member] | Phase III [Member]        
Product Liability Contingency [Line Items]        
Net sales     $ 100,000  
Enviro Cedars License Agreements [Member] | Phase III Clinical Trial [Member]        
Product Liability Contingency [Line Items]        
Net sales     $ 50,000