X0306 4 2022-12-15 0 0001001233 SANGAMO THERAPEUTICS, INC SGMO 0001955191 Beers Courtney C/O SANGAMO THERAPEUTICS, INC. 7000 MARINA BLVD. BRISBANE CA 94005 1 0 0 0 Common Stock 2022-12-15 4 A 0 18750 0.00 A 18750 D Stock Option (Right to Buy) 3.30 2022-12-15 4 A 0 37500 0.00 A 2032-12-14 Common Stock 37500 37500 D Represents shares of common stock issuable upon settlement of a restricted stock unit grant that will vest in three equal annual installments measured from the grant date, subject to the Reporting Person's Continuous Service (as defined in the Issuer's Amended and Restated 2018 Equity Incentive Plan, as amended (the "2018 EIP")), through each such date and subject to acceleration as provided in the 2018 EIP. The option is immediately exercisable in full, but any unvested shares that are purchased under the option are subject to certain repurchase rights by the Issuer upon cessation of the Reporting Person's Continuous Service (as defined in the 2018 EIP). The shares subject to the option will vest in 36 successive equal monthly installments following the grant date, subject to the Reporting Person's Continuous Service (as defined in the 2018 EIP) through each such date and subject to acceleration as provided in the 2018 EIP. Courtney Beers, by /s/ Ron A. Metzger, Attorney-in-Fact 2022-12-19