The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AKERO THERAPEUTICS INC | COM | 00973Y108 | BBG00L9211Y8 | 6,322,369 | 156,185 | SH | SOLE | 137,747 | 0 | 18,438 | ||
| ALKERMES PLC | SHS | G01767105 | BBG000C9F2F9 | 6,351,463 | 192,352 | SH | SOLE | 172,190 | 0 | 20,162 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | BBG000PLF6N0 | 2,194,379 | 268,919 | SH | SOLE | 268,919 | 0 | 0 | ||
| ARBUTUS BIOPHARMA CORP | COM | 03879J100 | BBG000RR8V85 | 1,632,908 | 467,882 | SH | SOLE | 275,086 | 0 | 192,796 | ||
| ARCELLX INC | COMMON STOCK | 03940C100 | BBG00QHJM4S9 | 17,959,574 | 273,774 | SH | SOLE | 234,358 | 0 | 39,416 | ||
| ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 | BBG00QN8K4M4 | 6,882,742 | 440,073 | SH | SOLE | 374,200 | 0 | 65,873 | ||
| ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 | BBG01SD8CN29 | 42,500 | 100,000 | SH | Call | SOLE | 100,000 | 0 | 0 | |
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 | BBG007R7VNC1 | 2,296,130 | 14,732 | SH | SOLE | 14,732 | 0 | 0 | ||
| BICARA THERAPEUTICS INC | COM | 055477103 | BBG00Z15DGK7 | 613,426 | 47,078 | SH | SOLE | 47,078 | 0 | 0 | ||
| BIOHAVEN LTD | COM | G1110E107 | BBG017BXV3Q9 | 6,023,559 | 250,564 | SH | SOLE | 219,822 | 0 | 30,742 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | BBG001MC8YF7 | 5,481,159 | 61,927 | SH | SOLE | 55,456 | 0 | 6,471 | ||
| BRIDGEBIO PHARMA INC | COM | 10806X102 | BBG00P9KDZK6 | 7,205,667 | 208,437 | SH | SOLE | 186,599 | 0 | 21,838 | ||
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 | BBG01081FC59 | 8,532,157 | 593,335 | SH | SOLE | 517,488 | 0 | 75,847 | ||
| CG ONCOLOGY INC | COM | 156944100 | BBG00YHKK4Q3 | 7,101,533 | 289,823 | SH | SOLE | 265,908 | 0 | 23,915 | ||
| CVS HEALTH CORP | COM | 126650100 | BBG01PVW5MX8 | 165,058 | 64,100 | SH | Put | SOLE | 64,100 | 0 | 0 | |
| CYTOKINETICS INC | COM NEW | 23282W605 | BBG000F0R4N9 | 6,014,353 | 149,648 | SH | SOLE | 131,440 | 0 | 18,208 | ||
| DENALI THERAPEUTICS INC | COM | 24823R105 | BBG008P7F869 | 9,068,925 | 667,078 | SH | SOLE | 582,358 | 0 | 84,720 | ||
| DYNE THERAPEUTICS INC | COM | 26818M108 | BBG00NSGPJD0 | 883,138 | 84,430 | SH | SOLE | 84,430 | 0 | 0 | ||
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | BBG00K4Y2H24 | 3,965,610 | 180,255 | SH | SOLE | 161,227 | 0 | 19,028 | ||
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | BBG01S7VXTL8 | 237,500 | 50,000 | SH | Put | SOLE | 50,000 | 0 | 0 | |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 | BBG00CP3BDD4 | 2,370,062 | 120,430 | SH | SOLE | 120,430 | 0 | 0 | ||
| ETFIS SER TR I | VIRTUS LIFESC CT | 26923G301 | BBG01S8PGCB7 | 16,563 | 132,500 | SH | Call | SOLE | 132,500 | 0 | 0 | |
| GERON CORP | COM | 374163103 | BBG000GX1891 | 1,526,888 | 960,307 | SH | SOLE | 859,649 | 0 | 100,658 | ||
| HELIX ACQUISITION CORP II | CL A ORD SHS | G4444H101 | BBG01L3GYF02 | 2,270,170 | 200,900 | SH | SOLE | 200,900 | 0 | 0 | ||
| IDEAYA BIOSCIENCES INC | COM | 45166A102 | BBG00CTZ4D83 | 1,097,444 | 66,999 | SH | SOLE | 66,999 | 0 | 0 | ||
| IMMUNOVANT INC | COM | 45258J102 | BBG00P5MC0Q8 | 14,585,836 | 853,472 | SH | SOLE | 734,474 | 0 | 118,998 | ||
| INFLARX NV | COM | N44821101 | BBG00HZ6PLC3 | 739,519 | 725,019 | SH | SOLE | 725,019 | 0 | 0 | ||
| INSMED INC | COM PAR $.01 | 457669307 | BBG000BWM5P3 | 6,641,731 | 87,059 | SH | SOLE | 77,957 | 0 | 9,102 | ||
| JANUX THERAPEUTICS INC | COM | 47103J105 | BBG00ZHSKH11 | 9,235,674 | 342,062 | SH | SOLE | 291,826 | 0 | 50,236 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | BBG0026ZG5B0 | 4,464,099 | 386,837 | SH | SOLE | 334,855 | 0 | 51,982 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | BBG01SF6XQH5 | 32,500 | 100,000 | SH | Call | SOLE | 100,000 | 0 | 0 | |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | BBG000QS6NV8 | 13,559,231 | 40,936 | SH | SOLE | 35,635 | 0 | 5,301 | ||
| MBX BIOSCIENCES INC | COM | 55287L101 | BBG00W7W53M5 | 713,019 | 96,615 | SH | SOLE | 96,615 | 0 | 0 | ||
| MERCK & CO INC | COM | 58933Y105 | BBG01P9CYYR6 | 8,344 | 151,700 | SH | Call | SOLE | 151,700 | 0 | 0 | |
| MERUS N V | COM | N5749R100 | BBG00B8LXMS5 | 14,594,960 | 346,756 | SH | SOLE | 310,564 | 0 | 36,192 | ||
| MINERALYS THERAPEUTICS INC | COM | 603170101 | BBG01RR46J49 | 93,750 | 125,000 | SH | Put | SOLE | 125,000 | 0 | 0 | |
| NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | BBG000GJS7C1 | 2,328,351 | 21,052 | SH | SOLE | 21,052 | 0 | 0 | ||
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 | BBG01BNNTQN4 | 2,140,855 | 104,585 | SH | SOLE | 89,695 | 0 | 14,890 | ||
| NOVO-NORDISK A S | ADR | 670100205 | BBG01Q3VMD15 | 3,793 | 151,700 | SH | Call | SOLE | 151,700 | 0 | 0 | |
| NUVALENT INC | COM | 670703107 | BBG00Z1SLMK5 | 13,503,239 | 190,401 | SH | SOLE | 162,961 | 0 | 27,440 | ||
| OCULAR THERAPEUTIX INC | COM | 67576A100 | BBG001J1BZV0 | 912,754 | 124,523 | SH | SOLE | 124,523 | 0 | 0 | ||
| PERCEPTIVE CAP SOLUTIONS COR | CL A ORD SHS | G70077105 | BBG01N0FG6L0 | 1,545,000 | 150,000 | SH | SOLE | 150,000 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | BBG002B63KM7 | 2,381,295 | 49,241 | SH | SOLE | 49,241 | 0 | 0 | ||
| PROTARA THERAPEUTICS INC | COM STK | 74365U107 | BBG001ZLYSH5 | 5,071,867 | 1,190,579 | SH | SOLE | 1,114,888 | 0 | 75,691 | ||
| REVOLUTION MEDICINES INC | COM | 76155X100 | BBG00829F4P8 | 11,272,132 | 318,782 | SH | SOLE | 268,947 | 0 | 49,835 | ||
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | BBG007DLZ601 | 1,791,234 | 33,816 | SH | SOLE | 33,816 | 0 | 0 | ||
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | BBG01P9PDCZ9 | 15,500 | 10,000 | SH | Call | SOLE | 10,000 | 0 | 0 | |
| ROIVANT SCIENCES LTD | SHS | G76279101 | BBG007STW2B8 | 26,020,697 | 2,578,860 | SH | SOLE | 2,368,791 | 0 | 210,069 | ||
| SCHOLAR ROCK HLDG CORP | COM | 80706P103 | BBG00KT2RRM6 | 18,203,716 | 566,212 | SH | SOLE | 485,795 | 0 | 80,417 | ||
| SIONNA THERAPEUTICS INC | COM | 829401108 | BBG016X2DC85 | 627,600 | 60,000 | SH | SOLE | 60,000 | 0 | 0 | ||
| SOLENO THERAPEUTICS INC | COM | 834203309 | BBG0024L5B86 | 797,025 | 11,155 | SH | SOLE | 11,155 | 0 | 0 | ||
| SOLID BIOSCIENCES INC | COM NEW | 83422E204 | BBG00JN4FXG8 | 733,155 | 198,150 | SH | SOLE | 198,150 | 0 | 0 | ||
| SPRINGWORKS THERAPEUTICS INC | COM | 85205L107 | BBG00Q011TW9 | 7,030,130 | 159,305 | SH | SOLE | 136,919 | 0 | 22,386 | ||
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | BBG0067L94B2 | 2,196,603 | 136,139 | SH | SOLE | 120,682 | 0 | 15,457 | ||
| SURROZEN INC | COM NEW | 86889P208 | BBG00XY94S95 | 2,808,031 | 240,826 | SH | SOLE | 197,835 | 0 | 42,991 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | BBG000R33JY1 | 19,638,727 | 1,598,594 | SH | SOLE | 1,431,721 | 0 | 166,873 | ||
| UNIQURE NV | SHS | N90064101 | BBG005SSJYH3 | 7,749,013 | 731,039 | SH | SOLE | 629,324 | 0 | 101,715 | ||
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 | BBG000BB33L9 | 737,176 | 616,749 | SH | SOLE | 616,749 | 0 | 0 | ||
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 | BBG000BB33L9 | 4,374,513 | 1,749,805 | SH | SOLE | 1,475,334 | 0 | 274,471 | ||
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 | BBG00B642V54 | 725,851 | 89,833 | SH | SOLE | 52,815 | 0 | 37,018 | ||
| XENON PHARMACEUTICALS INC | COM | 98420N105 | BBG0073DM784 | 9,213,937 | 274,633 | SH | SOLE | 246,188 | 0 | 28,445 | ||
| ZAI LAB LTD | ADR | 98887Q104 | BBG00HFX3N90 | 954,855 | 26,421 | SH | SOLE | 26,421 | 0 | 0 | ||