The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103 BBG00QKDZ8J5 4,560,231 408,257 SH   SOLE   408,257 0 0
AC IMMUNE SA SHS H00263105 BBG00D0RHJ38 2,172,940 434,588 SH   SOLE   434,588 0 0
ACELYRIN INC COM 00445A100 BBG00YJKJ8H4 4,381,803 587,373 SH   SOLE   394,076 0 193,297
ALPINE IMMUNE SCIENCES INC COM 02083G100 BBG001J2LL66 4,692,153 246,178 SH   SOLE   202,230 0 43,948
AMBRX BIOPHARMA INC COM 641871108 BBG0118LMRT6 1,795,678 126,101 SH   SOLE   126,101 0 0
AMICUS THERAPEUTICS INC COM 03152W109 BBG000PLF6N0 12,243,345 862,815 SH   SOLE   862,815 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 BBG00DP10YT5 1,227,368 83,381 SH   SOLE   83,381 0 0
ANAPTYSBIO INC COM 032724106 BBG0026ZDHR0 963,900 45,000 SH   SOLE   45,000 0 0
ANI PHARMACEUTICALS INC COM 00182C103 BBG000KK1L04 4,707,963 85,382 SH   SOLE   85,382 0 0
ANNEXON INC COM 03589W102 BBG007QVDFG2 2,756,234 607,100 SH   SOLE   607,100 0 0
APPLIED THERAPEUTICS INC COM 03828A101 BBG000DD0489 3,038,959 907,152 SH   SOLE   649,599 0 257,553
ARCELLX INC COMMON STOCK 03940C100 BBG01K0YQHF7 283,465 623 SH Call SOLE   623 0 0
ARCELLX INC COMMON STOCK 03940C100 BBG00QHJM4S9 17,405,022 313,604 SH   SOLE   282,067 0 31,537
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 BBG00QN8K4M4 8,380,351 2,594,536 SH   SOLE   2,059,616 0 534,920
ARGENX SE CALL 04016X901 BBG00GHB88X9 10,075,308 26,484 SH   SOLE   26,484 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302 BBG01KN9BR89 375,000 5,000 SH Put SOLE   5,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 BBG000BRVKH0 1,806,563 59,038 SH   SOLE   59,038 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   1,349,400 230,273 SH   SOLE   230,273 0 0
ASTRIA THERAPEUTICS INC COM 04635X102 BBG000QSGWX5 4,812,895 626,679 SH   SOLE   371,166 0 255,513
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 BBG00KVT05R6 2,906,855 451,375 SH   SOLE   358,700 0 92,675
BIOHAVEN LTD COM G1110E107 BBG017BXV3Q9 4,765,951 111,354 SH   SOLE   111,354 0 0
BRIDGEBIO PHARMA INC COM 10806X102 BBG00P9KDZK6 10,251,881 253,948 SH   SOLE   253,948 0 0
CABALETTA BIO INC COM 12674W109 BBG00MJ3BKW2 10,231,026 450,706 SH   SOLE   302,815 0 147,891
CARGO THERAPEUTICS INC COM 14179K101 BBG01D59LY25 622,156 26,875 SH   SOLE   26,875 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 BBG00BC59224 8,879,879 249,575 SH   SOLE   209,240 0 40,335
CYMABAY THERAPEUTICS INC COM 23257D103 BBG005NJY3N2 4,304,934 182,258 SH   SOLE   182,258 0 0
CYTOKINETICS INC COM NEW 23282W605 BBG000F0R4N9 2,013,027 24,111 SH   SOLE   24,111 0 0
DISC MEDICINE INC COM 254604101 BBG00W9MJK79 7,244,779 125,429 SH   SOLE   106,197 0 19,232
DISC MEDICINE INC COM 254604101   371,250 1,000 SH Call SOLE   1,000 0 0
ELI LILLY & CO COM 532457108 BBG000BNBDC2 8,782,856 15,067 SH   SOLE   15,067 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 BBG000F90JX5 2,212,367 95,732 SH   SOLE   85,020 0 10,712
FATE THERAPEUTICS INC COM 31189P102 BBG000QP35H2 3,359,253 898,196 SH   SOLE   633,516 0 264,680
FULCRUM THERAPEUTICS INC COM 359616109 BBG00DDY1RK9 2,541,868 376,573 SH   SOLE   326,048 0 50,525
IMMATICS N.V SHS N44445109 BBG00VTL2H76 10,742,853 1,020,214 SH   SOLE   780,583 0 239,631
IMMUNOVANT INC COM 45258J102 BBG00P5MC0Q8 13,566,492 322,015 SH   SOLE   263,603 0 58,412
INSMED INC COM PAR $.01 457669307 BBG000BWM5P3 5,379,213 173,579 SH   SOLE   173,579 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 BBG01KTLPLD8 231,600 600 SH Put SOLE   600 0 0
ISHARES TR ISHARES BIOTECH 464287556 BBG012M161Z0 360,000 2,000 SH Put SOLE   2,000 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 BBG01KMR3H81 573,750 1,500 SH Put SOLE   1,500 0 0
JASPER THERAPEUTICS INC CALL 471871903 BBG00QPZNP97 2,924,910 3,707,110 SH   SOLE   2,597,198 0 1,109,912
JOHNSON & JOHNSON COM 478160104 BBG000BMHYD1 9,562,864 61,011 SH   SOLE   61,011 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 BBG0026ZG5B0 5,183,882 423,174 SH   SOLE   319,288 0 103,886
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 BBG00KT2KFX7 3,211,609 183,102 SH   SOLE   183,102 0 0
LANTHEUS HLDGS INC COM 516544103 BBG006Q52RD0 6,752,482 108,911 SH   SOLE   108,911 0 0
LARIMAR THERAPEUTICS INC COM 517125100 BBG001J2NVH0 3,563,433 783,172 SH   SOLE   520,474 0 262,698
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 BBG00TTGH5W4 6,296,791 104,650 SH   SOLE   104,650 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 BBG000QS6NV8 4,730,333 20,444 SH   SOLE   20,444 0 0
MERCK & CO INC COM 58933Y105 BBG000BPD168 9,704,524 89,016 SH   SOLE   89,016 0 0
MERUS N V COM N5749R100 BBG00B8LXMS5 13,799,665 501,806 SH   SOLE   413,863 0 87,943
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 BBG01KBX9P95 335,000 500 SH Put SOLE   500 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 BBG00XQZQTS9 10,136,522 167,851 SH   SOLE   167,851 0 0
MORPHOSYS AG CALL 617760902 BBG00KN74FQ8 2,747,102 277,485 SH   SOLE   277,485 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 BBG000GJS7C1 2,964,600 22,500 SH   SOLE   22,500 0 0
OCULAR THERAPEUTIX INC COM 67576A100 BBG001J1BZV0 1,247,230 279,648 SH   SOLE   175,421 0 104,227
OLEMA PHARMACEUTICALS INC COM 68062P106 BBG00T5JMRT4 3,946,457 281,287 SH   SOLE   245,734 0 35,553
PROTAGONIST THERAPEUTICS INC COM 74366E102 BBG002B63KM7 11,778,705 513,681 SH   SOLE   513,681 0 0
RAPT THERAPEUTICS INC COM 75382E109 BBG00PGK50M2 1,452,483 58,450 SH   SOLE   58,450 0 0
ROIVANT SCIENCES LTD SHS G76279101 BBG007STW2B8 24,359,173 2,169,116 SH   SOLE   1,866,286 0 302,830
SAGE THERAPEUTICS INC COM 78667J108 BBG0025X16Y5 4,730,973 218,319 SH   SOLE   218,319 0 0
SCPHARMACEUTICALS INC COM 810648105 BBG00J24RT13 3,556,413 567,211 SH   SOLE   567,211 0 0
SHATTUCK LABS INC COM 82024L103 BBG00V776CQ7 1,053,472 147,752 SH   SOLE   147,752 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 BBG000BDTBL9 4,715,551 9,921 SH   SOLE   9,921 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   286,250 1,500 SH Put SOLE   1,500 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   902,250 5,000 SH Put SOLE   5,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202 BBG0067L94B2 8,151,044 378,766 SH   SOLE   313,378 0 65,388
SYNDAX PHARMACEUTICALS INC COM 87164F105 BBG000R33JY1 23,652,015 1,094,494 SH   SOLE   985,050 0 109,444
TARSUS PHARMACEUTICALS INC COM 87650L103 BBG00RB9BNQ7 627,548 30,990 SH   SOLE   30,990 0 0
TEVA PHARMACEUTICAL INDS LTD CALL 881624909 BBG000C0CD58 7,324,673 701,597 SH   SOLE   701,597 0 0
VISTAGEN THERAPEUTICS INC COM 92840H400   2,732,112 616,749 SH   SOLE   616,749 0 0
VISTAGEN THERAPEUTICS INC COM 92840H400 BBG000BB33L9 6,031,446 1,173,433 SH   SOLE   976,679 0 196,754